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مقالات فارسیISIکنفرانسهاژورنالها

Vitamin D Status in Osteoporotic and Diabetic Patients and Athletic Healthy Individuals from Northern Greece

محل انتشار: مجله گزارش های بیوشیمی و زیست شناسی مولکولی، دوره: 11، شماره: 4
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 83

فایل این مقاله در 12 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1664634

شناسه ملی سند علمی:

JR_RBMB-11-4_004

تاریخ نمایه سازی: 6 خرداد 1402

چکیده مقاله:

Background: Vitamin D deficiency is recognised as a pandemic in the developed world. However, the importance of prudent sun exposure tends to be overlooked, which is responsible for this pandemic. Methods: We investigated the vitamin D status in ۳۲۶ adults, ۱۶۵ females and ۱۶۱ males: ۹۹ Osteoporosis patients, ۵۳ Type ۱ Diabetes patients, ۵۱ Type ۲ Diabetes patients, and ۱۲۳ Athletic Healthy individuals, from Northern Greece, through the measurement of total calcidiol in winter and summer by immunoenzymatic assay. Results: In the Whole Sample ۲۳.۳۱% had severe deficiency, ۱۳.۵۰% mild deficiency, ۱۷.۴۸% insufficiency, and ۴۵.۷۱% adequacy at the end of winter. Mean concentrations differed significantly (p <۰.۰۰۱) between males and females. The prevalence of deficiency in the young was significantly lower than in the middle-aged (p = ۰.۰۰۴) and in the elderly (p <۰.۰۰۱), while it was significantly lower (p = ۰.۰۱۴) in the middle-aged than in the elderly. The best vitamin D status was found in the Athletic Healthy individuals, followed by the Type ۱ and Type ۲ Diabetic patients, while Osteoporotic patients had the poorest status. The difference in mean concentrations between winter and summer was significant (p <۰.۰۰۱). Conclusions: Vitamin D status deteriorated with increasing age and it was better in males than in females. Our findings suggest that outdoor physical activity in a Mediterranean country can cover the vitamin D needs of the young and the middle-aged, but not of the elderly, without the need for dietary supplements.

کلیدواژه ها:

Total calcidiol ، osteoporosis ، Type ۱ diabetes ، Type ۲ diabetes ، Vitamin D status.

نویسندگان

Constantine Anetakis

Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, ۵۷۴۰۰ Sindos, Thessaloniki, Greece.

Stella Mitka

Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, ۵۷۴۰۰ Sindos, Thessaloniki, Greece.

Maria Chatzidimitriou

Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, ۵۷۴۰۰ Sindos, Thessaloniki, Greece & Bioanalysis Diagnostic Laboratory, D. Gounari ۳۳, ۵۴۶۲۲ Thessaloniki

Konstantinos Anagnostopoulos

Faculty of Medicine, School of Health Sciences, Democritus University of Thrace, Greece.

Phaedra Eleftheriou

Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, ۵۷۴۰۰ Sindos, Thessaloniki, Greece.

Theodoros Lialiaris

Faculty of Medicine, School of Health Sciences, Democritus University of Thrace, Greece.

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