ورود
مقالات فارسیISIکنفرانسهاژورنالها

Recent advances in nanocarriers containing Bromelain: In vitro and in vivo studies

محل انتشار: مجله علوم نانو، دوره: 10، شماره: 3
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 88

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1684583

شناسه ملی سند علمی:

JR_NAMJ-10-3_001

تاریخ نمایه سازی: 11 تیر 1402

چکیده مقاله:

Medicinal products of plant origin have long been considered the most affordable and accessible sources to treat different health problems. Bromelain (Br) is a mixture of enzymes derived from pineapple (Ananas comosus L.) with a wide field of applications including medicine, health, food, and cosmetics. Br has various therapeutic effects, such as antimicrobial, antioxidant, anticancer, wound healing, burn treatment, pain relief, anti-inflammatory, inhibition of platelet aggregation, and fibrinolytic activity. On the other hand, most proteins are susceptible to denaturation and structural changes that may reduce their activities. Encapsulation of drug molecules into nanoparticles (NPs) could increase their stability, bioavailability, and overcome other challenges in drug delivery and therapy. This review aimed to highlight various Br nano-formulations approaches, toward the improvement of Br therapeutic efficiency.

کلیدواژه ها:

Bromelain ، Nanoparticles ، Pineapple ، Stability ، Therapeutic application

نویسندگان

Ashkan Safavinia

School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Sina Dehestani

Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA ۱۵۲۶۱, USA

Zahra Salmasi

Department of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Fatemeh Kalalinia

Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

Leila Etemad

Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

Maryam Hashemi

Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Pavan R, Jain S, Shraddha, Kumar A. Properties and therapeutic ...
  • Ataide JA, Gérios EF, Mazzola PG, Souto EB. Bromelain-loaded nanoparticles: ...
  • Rani A, Pannuru V. Unanticipated behaviour of sorbitol towards the ...
  • Silva C, Martins M, Jing S, Fu J, Cavaco-Paulo A. ...
  • Li J, Li M, Tang J, Li X, Zhang H, ...
  • Hami Z. A Brief Review on Advantages of Nano-based Drug ...
  • Gelperina S, Kisich K, Iseman MD, Heifets L. The potential ...
  • Parodi A, Haddix SG, Taghipour N, Scaria S, Taraballi F, ...
  • Bagga P, Ansari TM, Siddiqui HH, Syed A, Bahkali AH, ...
  • Khan S, Rizvi SMD, Avaish M, Arshad M, Bagga P, ...
  • de Sousa IP, Cattoz B, Wilcox MD, Griffiths PC, Dalgliesh ...
  • Samaridou E, Karidi K, de Sousa IP, Cattoz B, Griffiths ...
  • Ataide JA, Gérios EF, Cefali LC, Fernandes AR, Teixeira MdC, ...
  • Kammona O, Kiparissides C. Recent advances in nanocarrier-based mucosal delivery ...
  • Lü JM, Wang X, Marin-Muller C, Wang H, Lin PH, ...
  • Nagpal K, Singh SK, Mishra DN. Chitosan nanoparticles: a promising ...
  • Ahmed R, Tariq M, Ali I, Asghar R, Khanam PN, ...
  • Mala T, Anal AK. Protection and Controlled Gastrointestinal Release of ...
  • Brito AM, Oliveira V, Icimoto MY, Nantes-Cardoso IL. Collagenase activity ...
  • Singer AJ, Toussaint J, Chung WT, McClain SA, Clark RA, ...
  • Wickham N, Alexander KS, Fletcher A, O’Boyle C. Successful treatment ...
  • Hirche C, Almeland SK, Dheansa B, Fuchs P, Governa M, ...
  • Da Elisa Silva López R. Debridement applications of bromelain: a ...
  • Wu S-Y, Hu W, Zhang B, Liu S, Wang J-M, ...
  • Hikisz P, Bernasinska-Slomczewska J. Beneficial Properties of Bromelain. Nutrients. ۲۰۲۱;۱۳(۱۲):۴۳۱۳ ...
  • Ghensi P, Cucchi A, Bonaccorso A, Ferroni L, Gardin C, ...
  • Singer AJ, Taira BR, Anderson R, McClain SA, Rosenberg L. ...
  • Bayat S, Amiri N, Pishavar E, Kalalinia F, Movaffagh J, ...
  • Miranda ÍKSPB, Santana FR, Camilloto GP, Detoni CB, Souza FVD, ...
  • Bayat S, Zabihi AR, Farzad SA, Movaffagh J, Hashemi E, ...
  • Rachmawati H, Sulastri E, Immaculata Iwo M, Safitri D, Rahma ...
  • Hasannasab M, Nourmohammadi J, Dehghan MM, Ghaee A. Immobilization of ...
  • Ataide JA, Cefali LC, Figueiredo MC, Braga LEdO, Ruiz ALTG, ...
  • Wang X, He L, Wei B, Yan G, Wang J, ...
  • Nasiri R, Almaki JH, Idris A, Nasiri M, Irfan M, ...
  • Bhatnagar P, Patnaik S, Srivastava AK, Mudiam MK, Shukla Y, ...
  • Bhatnagar P, Pant AB, Shukla Y, Chaudhari B, Kumar P, ...
  • Karimian Rad F, Ramezani M, Mohammadgholi A. Physicochemical Properties of ...
  • Montazeri A, Ramezani M, Mohammadgholi A. Investigation the Effect of ...
  • Gaspani L, Limiroli E, Ferrario P, Bianchi M. In vivo ...
  • Bhui K, Prasad S, George J, Shukla Y. Bromelain inhibits ...
  • Hou RC-W, Chen Y-S, Huang J-R, Jeng K-CG. Cross-linked bromelain ...
  • Subramaniam V, Gardner H, Jothy S. Soluble CD۴۴ secretion contributes ...
  • Makrydimas G, Zagorianakou N, Zagorianakou P, Agnantis N. CD۴۴ family ...
  • Seligman B. Bromelain: an anti-inflammatory agent. Angiology. ۱۹۶۲;۱۳(۱۱):۵۰۸-۱۰ ...
  • Inoue K, Motonaga A, Dainaka J, Nishimura T, Hashii H, ...
  • Chakraborty AJ, Mitra S, Tallei TE, Tareq AM, Nainu F, ...
  • Sharma M, Chaudhary D. Exploration of bromelain laden nanostructured lipid ...
  • Bernela M, Ahuja M, Thakur R. Enhancement of anti-inflammatory activity ...
  • Shoba E, Lakra R, Kiran MS, Korrapati PS. ۳ D ...
  • Sahu M, Sharma AK, Sharma G, Kumar A, Nandave M, ...
    • نمایش کامل مراجع