Synthesis of Benzoxazole Derivatives Using Fe۳O۴@SiO۲-SO۳H Nanoparticles as a Useful and Reusable Heterogeneous Catalyst Without Using a Solvent

In the present study, a simple and rapid method using an effective heterogeneous nanomagnetic catalyst, Fe۳O۴@SiO۲-SO۳H, was used to prepare the ۲-arylbenzoxazoles derivatives by a condensation reaction of aromatic aldehydes with ۲-aminophenol without using solvent and at a temperature of ۵۰ ۰C. This catalyst is magnetically recycled and reused several times without reducing its catalytic activity. It was demonstrated that Fe۳O۴@SiO۲-SO۳H is an economic catalyst that can be used several times without reducing the catalytic properties. Purifying of the final products was simple and easy, and the percentage of catalyst performance was satisfactory.