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مقالات فارسیISIکنفرانسهاژورنالها

Poly (Lactic Acid) Nanoparticles: A Promising Hope to Overcome the Cancers

محل انتشار: مجله علوم پیشرفته زیست پزشکی، دوره: 11، شماره: 2
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 75

فایل این مقاله در 24 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1702312

شناسه ملی سند علمی:

JR_JABS-11-2_003

تاریخ نمایه سازی: 31 تیر 1402

چکیده مقاله:

Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid)(PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly.

کلیدواژه ها:

Poly (Lactic Acid) ، Polymeric Nanoparticle ، Cancer Treatment ، Drug Deliver ، Gene Delivery ، Tumor Cell

نویسندگان

فرنازالسادات فتاحی

Department of Textile Engineering, Isfahan University of Technology, Isfahan, Iran

طاهره زمانی

The Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran

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