Identification of Etiologic Agents of Actinomycetal Infections among Patients Referred to the Health Faculty of Tehran University of Medical Sciences
سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 64
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شناسه ملی سند علمی:
JR_IJMM-11-6_007
تاریخ نمایه سازی: 16 مرداد 1402
چکیده مقاله:
Background and Aims: Actinomycetes are a group of Gram-positive bacteria that have filamentous morphology with about one micron diameter. Actinomyces, Nocardia and Streptomyces are classified in this group. In this study, the etiological agents of actinomycetal infections were determined among patients referred to the Health faculty of Tehran University of Medical Sciences (TUMS).
Materials and Methods: To determine the status of actinomycetes diseases, ۴۶۵ specimens including the broncho-alveolar lavage (BAL), cerebrospinal fluid (CSF), tissue biopsy, abscess discharge and other clinical materiasl were examined via microscopic observation and culture methods. (۲۰۱۱-۲۰۱۵)
Results and Conclusions: Out of the ۴۶۵ specimens, ۲۰ (۴.۳%) were diagnosed as infected which included ۱۱(۵۵% ) Actinomyces and ۹ (۴۵% ) Nocardia. The most positive results were associated with pulmonary infections. Among the infected patients, ۶۰ % (۱۲) were male and ۴۰% (۸) were female. The results of this study showed that the prevalence of Actinomyces and Nocardia was similar, being more predominant among men compared to women. In order to obtain the appropriate results, it is recommended that samples are taken during doctor's visit and before starting a treatment. It is also recommended to use molecular methods such as PCR and RT-PCR for better identification and comparison with phenotypic methods.
کلیدواژه ها:
Actinomycosis ، Nocardiosis ، Actinomycetal ، BAL ، اکتینو مایکوزیس ، نوکاردیوزیس ، اکتینومایستال ، BAL
نویسندگان
Laleh Larijanian
Department of Microbiology, Faculty of Basic Sciences, Islamic Azad University, Science and Research Branch, Tehran, Iran
Jamal Hashemi
Department of Medical Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Davar Siadat
Department of Tuberculosis and Pulmonary Research, Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran
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