An Evaluation of Predictive Factors for Pulmonary Valve Replacement after Total Correction in Children with tetralogy of Fallot

سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 70

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شناسه ملی سند علمی:

JR_INJPM-11-7_005

تاریخ نمایه سازی: 25 مرداد 1402

چکیده مقاله:

Background: Congenital heart defects, with a prevalence of ۴-۸ cases per ۱۰۰۰ births, are one of the most common congenital defects. Tetralogy of Fallot (ToF) is the most common congenital cyanotic disease. There are several techniques for correcting this anomaly and ToF total correction is a routine option. Approximately ۴۰% of patients undergoing ToF, need Pulmonary Valve Replacement (PVR) in the years after primary surgery. In this study, we investigated the predictive factors of PVR in patients with ToF. Method: The participants included ۲۰۴ ToF patients who had undergone ToFTC surgery during ۲۰۰۴-۲۰۲۰. Many factors inducing age, sex, weight, pre-ToFTC echocardiographic findings, pre-ToFTC angiographic findings, pre-ToFTC palliative care, type of ToFTC surgery, and echocardiographic features of PVR were extracted and studied. Results: The mean age at ToFTC was ۲۷.۸ months in the PVR group and ۵۸.۸ months in ToFTC + PVR group (P < ۰.۰۰۱). Among echocardiographic findings before ToFTC surgery, RV function (P = ۰.۰۰۳), RPA (P = ۰.۰۱۵) and MPA (P = ۰.۰۳۶) were significantly different between the two groups. Valvotomy + VSD Closure surgery were significantly more prevalent among ToFTC patients (P = ۰.۰۰۱); however, Transannular Patch and Monocusp Implantation were done at higher rates among PVR patients. More palliative care before surgery was reported among PVR patients (P = ۰.۰۰۱), but ASD repair was more prevalent in the other group (P < ۰.۰۰۱) which was probably due to two more prevalence of ASD among patients of ToFTC group. Conclusion: Need for PVR surgery is affected by several factors, including demographic characteristics of patients and characteristics of surgical interventions, along with the anatomical and functional features of the heart.

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نویسندگان

Akbar Molaei

Pediatric Cardiology Department, Pediatric Health research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Maedeh Geybei

Medicine Doctor, Pediatric Health research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Shamsi Ghaffari

Pediatric cardiology Department, Pediatric Health research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Shahram Sadeghvand

Pediatric Health research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

MirHadi Mousavi

Pediatric Health research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Ahmad Khosroshahi

Pediatric cardiology Department, Pediatric Health research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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