Salivary Cortisol Associated with Increasing Mutans streptococci Count in Drug Abuser

سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 80

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شناسه ملی سند علمی:

JR_IJMM-17-3_006

تاریخ نمایه سازی: 1 شهریور 1402

چکیده مقاله:

Background and Aim: The aim of this study was to evaluate the relationship between salivary cortisol levels and the viable count of mutans streptococci in drug abusers. Materials and Methods: The study was conducted from March ۲۰۲۲ to May ۲۰۲۲ and included ۸۶ participants aged between ۱۷ to ۳۰ years, who were equally divided into two groups:  cases (n= ۴۳) and controls (n= ۴۳). All participants underwent a urine drug line test to confirm their drug use status. Saliva was collected, and centrifuged at ۳۰۰۰ for ۱۰ min, and the supernatant was stored at -۲۰°C for later estimation of salivary cortisol levels using a Cobas device. The viable count of Mutans streptococci was determined using an identification and culturing method to calculate the colony-forming units per milliliter (CFU/ml). Results: The drug abusers exhibited a significantly higher concentration of salivary cortisol as compared to the control group. In addition, the cases showed a positive correlation between salivary cortisol levels and the count of Mutans Streptococci. In contrast, the control group demonstrated a negative and non-significant relationship. Conclusion: The data from the current study indicated a higher concentration of salivary cortisol associated with an increasing count of Mutans streptococci compared to the control group.

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نویسندگان

Bilal A. Yassin

Department of Basic Sciences, College of Dentistry, University of Baghdad, Baghdad, Iraq

Abbas S. Al-Mizraqchi

Medical Microbiology, Department of Basic Sciences, College of Dentistry, University of Baghdad, Baghdad, Iraq

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