Effects of High Doses of X-Ray on Hematological Parameters and Morphology of Red Blood Cells in Human Blood

سال انتشار: 1398
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 55

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شناسه ملی سند علمی:

JR_IJMP-16-1_016

تاریخ نمایه سازی: 5 شهریور 1402

چکیده مقاله:

Introduction: The aim of the current study was to investigate the effects of X-ray radiation on some hematological parameters, morphology of red blood cells (RBC) and erythrocyte sedimentation rate (ESR) analysis of human blood using computed tomography (CT) scanner. Material and Methods: For the purpose of the study, ۵ ml of wholeblood was drawn from vein puncture of ۲۸ healthy people and divided into two equal parts in ethylendiamintetracetic acid (EDTA) tubes. The first ۲۸ tubes were assigned as the controls. The second ۲۸ tubes were divided into ۴ groups of ۷ cases, irradiated to (۳, ۶, ۹, and ۱۲) Gy, X-ray from a computed tomography CT-scan machine. Results: The results showed that no significant difference was observed for the hematological parameters and ESR analysis. However, there was a significant decrease in the radius of RBCs.In this regard, the mean RBC counts were obtained as  ۶.۲۶۷ ± ۰.۵۲۸, ۶.۸۶۷ ± ۰.۴۷۶, ۷.۱۶۷ ± ۰.۵۳۵, and ۶.۵۵ ± ۰.۲۹۵ μm after exposure to the radiation doses of ۳, ۶, ۹, and ۱۲ Gy, respectively. The crenation of the cells was also observed, and the percentage of crenation were <۵%, ۱۵%, ۴۰%, and ۶۰% after irradiation to ۳, ۶, ۹, and ۱۲ Gy, respectively. Conclusion: The in vitro irradiation of human blood to different X-ray doses (i.e.,۳, ۶, ۹, and ۱۲ Gy), resulted in the enhancement  of RBCs crenation  with increasing the dose, and reduction of the cell radius compared to those in the control groups. However, the hematological parameters and ESR analysis were not statistically affected.

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نویسندگان

Ali Taqi

Physics Department, College of Science, Kirkuk University, Kirkuk, Iraq.

kharmen Faraj

Department of Physics, College of Science, University of Sulaimani, Iraq

Sarah Zaynal

Department of Physics, College of Science, Kirkuk University, Kirkuk, Iraq

Jalil Said

CT Scan &amp; MRI Department, Kirkuk General Hospital, Kirkuk, Iraq

Ahmed Hameed

Hematology Laboratory, Kirkuk General Hospital, Kirkuk, Iraq

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