Effect of laser irradiation on the progression of skin cancer using carcinogen among hamsters

Introduction: Skin cancer has been increased day by day, but it can be cured if it diagnosed early. After reviewing the scientific literature about ۹۸۰ nm diode laser, and its multiple advantages on skin diseases. We studied in this paper the effectiveness of this type of laser on the progression of skin cancer among hamsters which were exposed to carcinogen on the back. Material and Methods: The carcinogenic solution of ۹, ۱۰-dime thy ۱-۱, ۲-benzanthracene was applied to the hamsters' skin on the back. A ۹۸۰ nm Diode laser light with irradiation power of ۰.۵w and ۱.۰w and an exposure time of ۱۰۰ sec were used in order to prevent the harmful thermal effect on surrounding tissue as studied in previous paper [۱]. Results: According to the results, only one group of hamsters which was not consistently irradiated by laser gave rise to melanoma tumor. The other groups that were exposed to diode ۹۸۰nm laser irradiation at different powers (i.e., ۰.۵w and ۱.۰w) and an exposure time of ۱۰۰ sec showed no growth of skin cancer during the experiment. Conclusion: The ۹۸۰ nm Diode laser has an effect on delaying the onset of cancer and has had a role in the reduction of skin cancer lesions. However, further studies are required to test its inhibitory activities against carcinogenesis.