ورود
مقالات فارسیISIکنفرانسهاژورنالها

Boosting therapeutic efficacy of mesenchymal stem cells in pulmonary fibrosis: The role of genetic modification and preconditioning strategies

محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 26، شماره: 9
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 79

فایل این مقاله در 15 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1738944

شناسه ملی سند علمی:

JR_IJBMS-26-9_003

تاریخ نمایه سازی: 5 شهریور 1402

چکیده مقاله:

Pulmonary fibrosis (PF) is the end stage of severe lung diseases, in which the lung parenchyma is replaced by fibrous scar tissue. The result is a remarkable reduction in pulmonary compliance, which may lead to respiratory failure and even death. Idiopathic pulmonary fibrosis (IPF) is the most prevalent form of PF, with no reasonable etiology. However, some factors are believed to be behind the etiology of PF, including prolonged administration of several medications (e.g., bleomycin and amiodarone), environmental contaminant exposure (e.g., gases, asbestos, and silica), and certain systemic diseases (e.g., systemic lupus erythematosus). Despite significant developments in the diagnostic approach to PF in the last few years, efforts to find more effective treatments remain challenging. With their immunomodulatory, anti-inflammatory, and anti-fibrotic properties, stem cells may provide a promising approach for treating a broad spectrum of fibrotic conditions. However, they may lose their biological functions after long-term in vitro culture or exposure to harsh in vivo situations. To overcome these limitations, numerous modification techniques, such as genetic modification, preconditioning, and optimization of cultivation methods for stem cell therapy, have been adopted. Herein, we summarize the previous investigations that have been designed to assess the effects of stem cell preconditioning or genetic modification on the regenerative capacity of stem cells in PF.

کلیدواژه ها:

Genetic modification ، Preconditioning ، Pulmonary Fibrosis ، Regenerative capacity ، Stem cells

نویسندگان

Mehrnaz Mehrabani

Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

Sohaib Mohammadyar

Department of Laboratory Hematology and Blood Banking, Faculty of Allied Medicine, Kerman University of Medical Sciences, Kerman, Iran

Mohammad Amin Rajizadeh

Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

Mohammad- Abbas Bejeshk

Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

Bahareh Ahmadi

Department of Laboratory Hematology and Blood Banking, Faculty of Allied Medicine, Kerman University of Medical Sciences, Kerman, Iran

Mohammad Hadi Nematollahi

Applied Cellular and Molecular Research Center, Kerman University of Medical Sciences, Kerman, Iran

Maryamossadat Mirtajaddini Goki

Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran

Kobra Bahrampour Juybari

Abnormal Uterine Bleeding Research Center, Semnan University of Medical Sciences, Semnan, Iran

Arian Amirkhosravi

Pharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Wuyts WA, Agostini C, Antoniou KM, Bouros D, Chambers R, ...
  • Xu J, Li L, Xiong J, Zheng Y, Ye Q, ...
  • Rafii R, Juarez MM, Albertson TE, Chan AL. A review ...
  • Ruigrok MJ, Frijlink HW, Melgert BN, Olinga P, Hinrichs WL. ...
  • Poursalehi HR, Fekri MS, Far FS, Mandegari A, Izadi A, ...
  • Javad-Mousavi SA, Hemmati AA, Mehrzadi S, Hosseinzadeh A, Houshmand G, ...
  • Mehrabani M, Goudarzi M, Mehrzadi S, Siahpoosh A, Mohammadi M, ...
  • Samareh Fekri M, Mandegary A, Sharififar F, Poursalehi HR, Nematollahi ...
  • Samareh-Fekri M, Poursalehi H-R, Mandegary A, Sharififar F, Mahmoudi R, ...
  • Mehrzadi S, Hosseini P, Mehrabani M, Siahpoosh A, Goudarzi M, ...
  • McNulty K, Janes SM. Stem cells and pulmonary fibrosis: cause ...
  • Ortiz LA, DuTreil M, Fattman C, Pandey AC, Torres G, ...
  • Ortiz LA, Gambelli F, McBride C, Gaupp D, Baddoo M, ...
  • Kumamoto M, Nishiwaki T, Matsuo N, Kimura H, Matsushima K. ...
  • Epperly MW, Guo H, Gretton JE, Greenberger JS. Bone marrow ...
  • Zakrzewski W, Dobrzyński M, Szymonowicz M, Rybak Z. Stem cells: ...
  • Wu R, Hu X, Wang Ja. Concise review: optimized strategies ...
  • Mirzamohammadi S, Mehrabani M, Tekiyehmaroof N, Sharifi A. Protective effect ...
  • Bahrampour Juybari K, Kamarul T, Najafi M, Jafari D, Sharifi ...
  • Safari S, Eidi A, Mehrabani M, Fatemi MJ, Sharifi AM. ...
  • Putri WE, Endaryanto A, Rantam FA, Prakoeswa CRS. Mesenchymal stem ...
  • Mirzamohammadi S, Aali E, Najafi R, Kamarul T, Mehrabani M, ...
  • Herberts CA, Kwa MS, Hermsen HP. Risk factors in the ...
  • Juybari KB, Pourhanifeh MH, Hosseinzadeh A, Hemati K, Mehrzadi S. ...
  • Najar M, Bouhtit F, Melki R, Afif H, Hamal A, ...
  • Aminzadeh A, Maroof NT, Mehrabani M, Juybari KB, Sharifi AM. ...
  • Wang Y, Zhang Z, Chi Y, Zhang Q, Xu F, ...
  • Robey TE, Saiget MK, Reinecke H, Murry CE. Systems approaches ...
  • Hu C, Li L. Preconditioning influences mesenchymal stem cell properties ...
  • Shafiq M, Jung Y, Kim SH. Insight on stem cell ...
  • Moeinabadi-Bidgoli K, Babajani A, Yazdanpanah G, Farhadihosseinabadi B, Jamshidi E, ...
  • Averyanov A, Koroleva I, Konoplyannikov M, Revkova V, Lesnyak V, ...
  • Campo A, González-Ruiz JM, Andreu E, Alcaide AB, Ocón MM, ...
  • Glassberg MK, Minkiewicz J, Toonkel RL, Simonet ES, Rubio GA, ...
  • Tzouvelekis A, Paspaliaris V, Koliakos G, Ntolios P, Bouros E, ...
  • Liu W, Wang H, Yu W, Bi X, Chen J, ...
  • Wu J, Zhou X, Tan Y, Wang L, Li T, ...
  • Chambers DC, Enever D, Ilic N, Sparks L, Whitelaw K, ...
  • Kim SH, Moon H-H, Kim HA, Hwang K-C, Lee M, ...
  • Cheng Z, Ou L, Zhou X, Li F, Jia X, ...
  • Borden BA, Yockman J, Kim SW. Thermoresponsive hydrogel as a ...
  • Yang S, Liu P, Jiang Y, Wang Z, Dai H, ...
  • Marofi F, Vahedi G, Biglari A, Esmaeilzadeh A, Athari SS. ...
  • Shahror RA, Wu C-C, Chiang Y-H, Chen K-Y. Genetically modified ...
  • Schäfer R, Spohn G, Baer PC. Mesenchymal stem/stromal cells in ...
  • Li X, An G, Wang Y, Liang D, Zhu Z, ...
  • Manson SR, Song JB, Hruska KA, Austin PF. HDAC dependent ...
  • Wang L-P, Dong J-Z, Xiong L-J, Shi K-Q, Zou Z-L, ...
  • Urbina P, Singla DK. BMP-۷ attenuates adverse cardiac remodeling mediated ...
  • Grimminger F, Günther A, Vancheri C. The role of tyrosine ...
  • Ono M, Ohkouchi S, Kanehira M, Tode N, Kobayashi M, ...
  • Marshall RP, Gohlke P, Chambers RC, Howell DC, Bottoms SE, ...
  • Imai Y, Kuba K, Rao S, Huan Y, Guo F, ...
  • Min F, Gao F, Li Q, Liu Z. Therapeutic effect ...
  • Liu D, Kong F, Yuan Y, Seth P, Xu W, ...
  • Rojas M, Xu J, Woods CR, Mora AL, Spears W, ...
  • Ishizawa K, Kubo H, Yamada M, Kobayashi S, Numasaki M, ...
  • Gazdhar A, Susuri N, Hostettler K, Gugger M, Knudsen L, ...
  • Cahill EF, Kennelly H, Carty F, Mahon BP, English K. ...
  • Li X, Wang Y, An G, Liang D, Zhu Z, ...
  • Lan Y-W, Theng S-M, Huang T-T, Choo K-B, Chen C-M, ...
  • Morikawa O, Walker TA, Nielsen LD, Pan T, Cook JL, ...
  • Xie T, Liang J, Geng Y, Liu N, Kurkciyan A, ...
  • Aguilar S, Scotton CJ, McNulty K, Nye E, Stamp G, ...
  • Han J, Liu Y, Liu H, Li Y. Genetically modified ...
  • Kwon O-S, Kim K-T, Lee E, Kim M, Choi S-H, ...
  • Roderburg C, Luedde T. Circulating microRNAs as markers of liver ...
  • Chen K, Boettiger A, Moffitt J, Wang S, Zhuang X. ...
  • Li Q, Zhang D, Wang Y, Sun P, Hou X, ...
  • Li P, Li J, Chen T, Wang H, Chu H, ...
  • Xie T, Liang J, Guo R, Liu N, Noble PW, ...
  • Maltby S, Plank M, Tay HL, Collison A, Foster PS. ...
  • Liu G, Friggeri A, Yang Y, Milosevic J, Ding Q, ...
  • Wang C, Gu S, Cao H, Li Z, Xiang Z, ...
  • Pottier N, Maurin T, Chevalier B, Puisségur M-P, Lebrigand K, ...
  • Yang S, Banerjee S, de Freitas A, Sanders YY, Ding ...
  • Liang H, Xu C, Pan Z, Zhang Y, Xu Z, ...
  • Ji X, Wu B, Fan J, Han R, Luo C, ...
  • Huleihel L, Sellares J, Cardenes N, Álvarez D, Faner R, ...
  • Chen X, Shi C, Wang C, Liu W, Chu Y, ...
  • Shi L, Han Q, Hong Y, Li W, Gong G, ...
  • Laganà A, Veneziano D, Russo F, Pulvirenti A, Giugno R, ...
  • Monga I, Qureshi A, Thakur N, Gupta AK, Kumar M. ...
  • Fernandes F, Kotharkar P, Chakravorty A, Kowshik M, Talukdar I. ...
  • Hou J, Ji Q, Ji J, Ju S, Xu C, ...
  • Williford J-M, Wu J, Ren Y, Archang MM, Leong KW, ...
  • Tsai L-R, Chen M-H, Chien C-T, Chen M-K, Lin F-S, ...
  • Feng L, Yang X, Shi X, Tan X, Peng R, ...
  • Ji Q, Hou J, Yong X, Gong G, Muddassir M, ...
  • Chen X, Shi C, Cao H, Chen L, Hou J, ...
  • Shi C, Chen X, Yin W, Sun Z, Hou J, ...
  • Wu G, Chang F, Fang H, Zheng X, Zhuang M, ...
  • Saparov A, Ogay V, Nurgozhin T, Jumabay M, Chen WC. ...
  • Mehrabani M, Najafi M, Kamarul T, Mansouri K, Iranpour M, ...
  • Haider HK, Ashraf M. Preconditioning and stem cell survival. J ...
  • Francis K, Wei L. Human embryonic stem cell neural differentiation ...
  • Takeda K, Ning F, Domenico J, Okamoto M, Ashino S, ...
  • Wang H, Yang YF, Zhao L, Xiao FJ, Zhang QW, ...
  • Petrella F, Coccè V, Masia C, Milani M, Salè EO, ...
  • Horie S, Gaynard S, Murphy M, Barry F, Scully M, ...
  • Li D, Liu Q, Qi L, Dai X, Liu H, ...
  • Antebi B, Rodriguez LA, Walker KP, Asher AM, Kamucheka RM, ...
  • Zhang W, Liu L, Huo Y, Yang Y, Wang Y. ...
  • Hu X, Yu SP, Fraser JL, Lu Z, Ogle ME, ...
  • Theus MH, Wei L, Cui L, Francis K, Hu X, ...
  • Jaussaud J, Biais M, Calderon J, Chevaleyre J, Duchez P, ...
  • Chang CP, Chio CC, Cheong CU, Chao CM, Cheng BC, ...
  • Mottaghi S, Larijani B, Sharifi AM. Apelin ۱۳: a novel ...
  • Yu J, Yin S, Zhang W, Gao F, Liu Y, ...
  • Tsai C-C, Yew T-L, Yang D-C, Huang W-H, Hung S-C. ...
  • Liu L, Gao J, Yuan Y, Chang Q, Liao Y, ...
  • McLaren AT, Marsden PA, Mazer CD, Baker AJ, Stewart DJ, ...
  • Mehrabani M, Nematollahi MH, Tarzi ME, Juybari KB, Abolhassani M, ...
  • McGettrick AF, O’Neill LA. The role of HIF in immunity ...
  • Fábián Z. The effects of hypoxia on the immune-modulatory properties ...
  • Liu YY, Chiang CH, Hung SC, Chian CF, Tsai CL, ...
  • Lan YW, Choo KB, Chen CM, Hung TH, Chen YB, ...
  • Kitajima Y, Ide T, Ohtsuka T, Miyazaki K. Induction of ...
  • Lan YW, Theng SM, Huang TT, Choo KB, Chen CM, ...
  • Zhao F, Liu W, Yue S, Yang L, Hua Q, ...
  • Zhao FY, Cheng TY, Yang L, Huang YH, Li C, ...
  • Rozier P, Maumus M, Maria ATJ, Toupet K, Jorgensen C, ...
  • Ryan J, Barry F, Murphy J, Mahon BP. Interferon-γ does ...
  • Sheng H, Wang Y, Jin Y, Zhang Q, Zhang Y, ...
  • Yao L, Liu Cj, Luo Q, Gong M, Chen J, ...
  • Wang Q, Shen C, Zhu H, Zhou W-G, Guo X-C, ...
  • Mahmoudi T, Abdolmohammadi K, Bashiri H, Mohammadi M, Rezaie MJ, ...
  • Dave A, Kar S, Banerjee ER. Effect of CoCl۲ or ...
  • Peng X, Li X, Li C, Yue S, Huang Y, ...
  • Li X, Li C, Tang Y, Huang Y, Cheng Q, ...
    • نمایش کامل مراجع