A mild, efficient green methodology for the Boc protection of aminescarried out at room temperature using silica boron sulfonic acid asthe catalyst

A simple, versatile and eco- friendly protocol for the N-Boc protection of various amines with di- tert- butyldicarbonate using silica boron sulfonic acid as the catalyst is described. The catalyst can be readily separated fromthe reaction products by simple filtration, Solvent less condition, easy work-up and good yields are the strikingfeatures of this methodology.