Catalytic effect of green zinc oxide nanoparticles on multi –componentreactions

In this study, multi component Hantzsch reaction was carried out between various Aromatic Aldehyde withDimedone,Ethyl acetate and ammonium acetate to produce polyhydroquinoline derivatives under solvent-freeconditions at ۱۱۰oC by a (Zinc oxide nanocatalyst) as effective Lewis acid. The remarkable advantages offeredby this method compared with other methods are a green catalyst, simple work-up procedures, fast reactions, along high yields.