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مقالات فارسیISIکنفرانسهاژورنالها

Shigella Antibiotic Resistance in Pediatric Shigellosis Infection: A Retrospective Study in Hormozgan, Iran

محل انتشار: مجله بین المللی کودکان، دوره: 11، شماره: 8
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 109

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لینک ثابت به این مقاله:
https://civilica.com/doc/1765875

شناسه ملی سند علمی:

JR_INJPM-11-8_005

تاریخ نمایه سازی: 3 مهر 1402

چکیده مقاله:

Background: Shigella is a gram-negative, facultative anaerobic, nonperforming, nonmotile and rod-shaped bacterium that causes mucoid bloody diarrhea, known as dysentery or shigellosis. This study aimed to determine the prevalence of Shigella species and the antibiotic resistance pattern of Shigella species isolated from children with acute diarrhea in Bandar Abbas Pediatric Hospital, south of Iran.Method: This descriptive and retrospective study was conducted based on the patients’ information in their checklists, including age, gender, Shigella culture results, Shigella species, cessation of fever, city of residence, duration of symptoms before hospitalization, antibiotic use in the previous two weeks, degree of fever at the time of hospitalization, vomiting, convulsions, dehydration, death, frequency of diarrhea, and loss of blood in feces.Results: Out of ۱۶۲ patients, ۸۲ (۵۰.۶۲%) were females, and ۸۰ (۴۹.۳۸%) were males. Cultures of ۴۶ patients (۲۸.۳۹%) were infected with Shigella flexneri species, ۶ patients (۳.۷۲%) with Shigella boydii species, and ۵۶ patients (۳۴.۵۸%) with Shigella sonnei species. Tetracycline had the highest rate of resistance (۸۸.۸%), and ciprofloxacin had the lowest resistance (۷.۴۱%).Conclusion: The pattern of common Shigella species has changed from S. flexneri to S. sonnei in recent years. The pattern of antibiotic resistance among these species is also changing; so regular investigation of the prevalence of different species and their drug resistance pattern is necessary to make a correct decision about the appropriate treatment.

کلیدواژه ها:

Antimicrobial resistance ، ، ، ، ، Shigella flexneri ، ، ، ، ، Shigella sonnei ، ، ، ، ، Dysentery ، ، ، ، ، Treatment

نویسندگان

Aida Razavi

Student Research Committee, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Zahra Tavasoli

Ghaemieh health care center, Mazandaran University of Medical Sciences, Sari,Iran.

Marjan Tariverdi

Department of Pediatrics, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Mohammad Tamaddondar

Department of Nephrology, Hormozgan University of Medical Sciences, Bandar-Abbas, Iran

Ali Rahnama Sisakht

Student Research Committee, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Azin Tavasoli

Department of Neuroscience, university of California San Diego, California, United State Amarica.

Mohammad Satarzadeh

Student Research Committee , Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

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