A One-Pot Synthesis of Some Novel Ethyl ۲-((۱H-Benzo[d]imidazol-۲-ylamino)(Aryl)methylthio)acetates by Nano-CuY Zeolite as an Efficient and Eco-Friendly Nanocatalyst
محل انتشار: دوفصلنامه تحقیقات شیمی آلی، دوره: 1، شماره: 1
سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 48
فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_ORGC-1-1_009
تاریخ نمایه سازی: 3 مهر 1402
چکیده مقاله:
A one-pot multicomponent reaction of aryl aldehydes, ۲-amino benzimidazole and ethyl ۲-mercaptoacetate is described as an efficient and environmentally method for the synthesis of some novel ethyl ۲-((۱H-benzo[d]imidazol-۲-ylamino)(Aryl)methylthio) acetates in the presence of nano-Copper Y Zeolite (NCZ) as a catalyst in ethanol at room temperature. After optimizing of reaction conditions for this reaction, the amount of catalyst obtained was ۱۰W%. The yield of reactions was in the range of ۷۵-۸۹%. The synthesized compounds ۴a-j were characterized using IR, ۱H NMR, ۱۳C NMR spectroscopy and Elemental Analysis. The present procedure offers several advantages, such as use of available, safety and reusable of the catalyst, high yields, short reaction times, easy and quick isolation of the product. This method may provide a developed groundwork for the synthesis of new commercial fungicide Benomyl and Carbendazim derivatives. Also, this procedure may be used as a synthetic pathway for preparation of new sulfur-bearing peptide derivatives based on ۲-amino benzimidazole core under mild conditions.
کلیدواژه ها:
نویسندگان
Mehdi Kalhor
Department of chemistry, Payame Noor University