Evaluation of the low-Frequency Eelectromagnetic Fields on Biochemical Parameters in the Absence and Presence of Vitamin C in Mice
محل انتشار: فصلنامه پزشکی شخصی، دوره: 8، شماره: 30
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 83
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شناسه ملی سند علمی:
JR_PMJ-8-30_003
تاریخ نمایه سازی: 15 مهر 1402
چکیده مقاله:
Exposure to low-frequency electromagnetic fields (LF-EMF) has been considered a global concern because of its harmful effects on human health (cancer, neurodegenerative disorders, etc.). According to the International Agency for Research on Cancer, EMF has been classified as a possible cancerous element for human health. Antioxidants such as vitamin C improve the damage caused by EMF by reducing oxidative stress. To evaluate the effects of EMF on the serum total protein, blood sugar, albumin and triglyceride, and the inhibitory role of vitamin C, ۴۰ male BALB/c mice were recruited. Participants were randomly distributed into four groups ۱- exposure to LF-EMF, ۲- exposure to LF-EMF which received vitamin C (۵۰ mg/kg), ۳- exposure to LF-EMF which received vitamin C (۱۰۰ mg/kg), and ۴- control group (no exposure). The experimental groups (۱-۳) received LF-EMF (۵۰ Hz, ۴ mT, ۴ hours/day, and ۱ month) while both groups ۲ and ۳ had intraperitoneally injected vitamin C (۵۰ mg/kg, ۱۰۰ mg/kg) every other day basis respectively. The obtained results demonstrated higher triglyceride and total protein levels and lower albumin and blood sugar levels in the LF-EMF group compared to controls while vitamin C restricts their alterations (p<۰.۰۵). To sum it up, our data show that intraperitoneal injection of vitamin C restricts the effects of LF-EMF exposure on the biochemical parameters in mice. However, the antioxidant characteristics of vitamin C may be probably involved in the LF-EMF effects of biochemical parameters in mice.
کلیدواژه ها:
نویسندگان
Melika Parsianmehr
Department of Biology, Faculty of Science, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Ali Neamati
Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran
Masoud Homayouni Tabrizi
Department of Biology, Faculty of Science, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Sahar Abareshi
Department of Biology, Faculty of Science, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Parisa Sanati
Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, ۷۱۳۴۵-۱۹۷۸,Shiraz, Iran.