Anti-anxiety and antioxidant properties of the zinc nanoparticles green-formulated by an ethnomedicinal plant in the in vivo condition

سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 76

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شناسه ملی سند علمی:

JR_PBP-5-2_002

تاریخ نمایه سازی: 10 آبان 1402

چکیده مقاله:

Objectives: One of the application areas of nanobiotechnology is the use of silver nanoparticles (Nanosilver particles) for a new solution in medical treatments. In the present study, the researchers investigate the effect of nano silver particles of the aqueous extract of Artemisia aucheri on skin wound healing among male rats. Material and Methods: After creating wounds in ۴۸ rats, they were randomly divided into ۶ groups. Treated with ۰.۲% AgNPs ointment, ۰.۲% AgSO۴ ointment,   ۰.۲% A. aucheri  ointment, ۳% tetracycline ointment, Eucerin basal ointment, and untreated control group. The tested groups were treated for ten days. Results: Treatment with AgNPs ointment significantly increased the amount of vascular contraction, hexose amine and hydroxyproline, and fibrocyte and fibrocyte to fibroblast ratio. Also, in the mentioned group, the wound area and the total number of cells, neutrophils and lymphocytes decreased significantly compared to other groups.  Conclusion: The nano silver particles of the aqueous extract of A. aucheri accelerate the healing process of skin wounds and reduce the time required for complete wound healing.

نویسندگان

Seyed Morteza Hosseini

Medicine, Quran and Hadith Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Namdar yousofvand

Department of Biology, Faculty of Science, Razi University, ۶۷۱۴۹-۶۷۳۴۶, Kermanshah, Iran

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