Fungal Rhinosinusitis: Study of Risk Factors, Outcome and Utility of Nasal Samples in Its Diagnosis
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 60
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شناسه ملی سند علمی:
JR_IJMM-17-4_002
تاریخ نمایه سازی: 13 آبان 1402
چکیده مقاله:
Background and Aim: Fungal rhinosinusitis (FRS) sets in following interactivity of fungi with Sino nasal tract when immune system is subdued. Due to varied clinical presentation of FRS with inconclusive evidence of imaging, mycological evaluation helps to identify and speciate the fungi .FRS can be diagnosed with biopsy tissue and/or deep nasal swabs. This study was undertaken to know risk factors, outcome along with utility of nasal samples with emphasis on deep nasal swabs in diagnosing fungal rhinosinusitis.
Materials and Methods: A retrospective observational study was carried out on patients with suspected fungal rhinosinusitis (invasive and non-invasive). Both COVID ۱۹ positive and negative patients by RT-PCR were included. Brief clinical history, associated comorbidities, risk factors and outcome were noted in these cases. Nasal swabs or tissue sample from endoscopic biopsy obtained from patients were subjected to Gram stain, KOH mount and culture on Sabouraud dextrose agar followed by slide culture for identification.
Results: Of the ۴۱ cases studied for FRS, ۲۵ were males and ۱۶ females. Risk factors like Post COVID-۱۹ infection was seen in ۲۷(۶۵.۸%), diabetes in ۳۱(۷۵.۶%) and use of steroid during COVID-۱۹ treatment in ۱۶(۳۹.۰۲%) cases. Deep nasal swabs were received in ۲۹(۷۰.۷%) and tissue obtained after debridement in ۱۲(۲۹.۳%) cases. Rhizopus spp was the most common fungi isolated followed by Aspergillus spp.
Conclusion: Both COVID and non-COVID patients were diagnosed with invasive/ non-invasive fungal rhinosinusitis from deep nasal swabs/tissue in the present study. Diabetes was an important comorbidity in non-COVID patients with FRS. Deep nasal swabs aided early diagnosis for both invasive and non-invasive FRS.
کلیدواژه ها:
نویسندگان
Dhanashree P Inamdar
Department of Microbiology, Mamata Medical College and Hospital, Khammam, India
Preeti U Deshpande
Department of Microbiology, Mamata Medical College and Hospital, Khammam, India
Anuradha Basavaraju
Department of Microbiology, Mamata Medical College and Hospital, Khammam, India
Nagapraveen Veerapu
Department of Community Medicine, Government Medical College (GMC), Anantapuramu, India
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