The Effect of Oral Selenium on the Size of Thyroid Nodules in Patients with Benign Thyroid nodules: A Brief Study

Objective: The thyroid gland is susceptible to the formation of nodules. Therefore, due to the critical role of selenium in the function of the thyroid gland, the impact of this element on the size and volume of this organ and its nodules were examined. Materials and Methods: During three months, two groups consisting of ۳۰ patients with benign thyroid nodules who were referred to Baghaeipour Endocrinology Clinic were given daily doses of ۱۰۰ and ۲۰۰ micrograms of selenium, and a control group of ۳۰ people without selenium consumption were assessed. Results: The results of intergroup analysis detected that the mean (±SD) of nodules length in the ۱۰۰ µg selenium consumer group was ۱۷.۱۳ (±۷.۹) and ۱۴.۹۳ (±۶.۰۱) before and after intervention respectively (P= ۰.۰۰۸). About the nodules height in the ۲۰۰ µg selenium consumer group, the mean (±SD) was ۹.۳ (±۲.۸) and ۸.۹۳ (±۲.۷۱) before and after intervention in that order (P= ۰.۰۰۱). Conclusion: Our findings suggest that selenium has been effective in the size and volume of the nodule and thyroid gland, as well as the TSH hormone, and further studies are needed to determine its therapeutic approach and efficacy.