The effect of the hexanic extracts of fig (Ficus carica) and olive (Olea europaea) fruit and nanoparticles of selenium on the immunogenicity of the inactivated avian influenza virus subtype H۹N۲
محل انتشار: گفتمان پژوهش دامپزشکی، دوره: 6، شماره: 3
سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 59
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شناسه ملی سند علمی:
JR_VRFAN-6-3_008
تاریخ نمایه سازی: 25 آبان 1402
چکیده مقاله:
Influenza is a contagious viral disease that is seen in avian, human and other mammals, so its control is important. Vaccination against influenza virus subtype H۹N۲ is one of the ways in controlling program, for this reason several vaccines has been produced. Recently, application of inactivated oil-emulsion vaccines in poultry for controlling low pathogenic avian influenza is increasing. At present, oils that are used as adjuvant in commercial vaccines are mineral oils, which not only lack immunizing effect, but also produce some detriments. The aim of this study is the evaluation the immunogenicity of vegetable oils, which are more metabolizable and safer than mineral oils. In this study the efficacy of hexanic extracts of fig (Ficus carica) and olive (Olea europaea) fruit and also nano-selenium on the immunogenicity of the inactivated avian influenza virus subtype H۹N۲ was evaluated in broiler chickens. The results indicated that the prepared emulsions could elicit a little degree of immunity, but they could not inhibit the anamnestic response and infection. With regard to the results, it seems that the intact mixture of fig and olive fruit hexanic extracts could not be administered as an immunoadjuvant in the vaccine, and about nano-selenium. In spite of positive effect on the immunogenicity of avian influenza virus subtype H۹N۲, it still needs more work.
کلیدواژه ها:
نویسندگان
Amir Hossein Asl Najjari
Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
Zolfaghar Rajabi
Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
Mehdi Vasfi Marandi
Department of Avian Diseases, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Gholamreza Dehghan
Department of Biology, Faculty of Sciences, University of Tabriz, Tabriz, Iran
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