ورود
مقالات فارسیISIکنفرانسهاژورنالها

Direct pulp capping with autologous bone marrow derived stem cells in dogs

محل انتشار: گفتمان پژوهش دامپزشکی، دوره: 13، شماره: 2
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 78

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1818728

شناسه ملی سند علمی:

JR_VRFAN-13-2_007

تاریخ نمایه سازی: 25 آبان 1402

چکیده مقاله:

Bone-marrow derived stem cells (BMSCs) can differentiate into several mesenchymal cell lines and are suitable candidates for bone and dental tissue engineering. This study aimed to assess the efficacy of cell therapy in direct pulp capping (DPC) of canine teeth using autologous BMSCs along with collagen/hydroxyapatite hybrid scaffold in terms of the quantity and quality of calcified bridge formation. The teeth were randomly divided into three groups of DPC with mineral trioxide aggregate (MTA), hydroxyapatite/collagen hybrid scaffold alone and BMSCs with hydroxyapatite/collagen hybrid scaffold; DPC was performed under general anesthesia in cavities prepared on the buccal surfaces of mandibular and maxillary premolars of the same dogs from which, stem cells had been isolated. All cavities were then restored with light-cure resin modified glass ionomer cement. Histomorphometric assessments after ۱۲ weeks showed formation of dentinal bridge following DPC with BMSCs and MTA. The efficacy of MTA for calcified bridge formation following DPC was significantly higher than that of BMSCs plus hybrid scaffold (P<۰.۰۰۰۱). According to present study, we concluded DPC using BMSCs and hybrid scaffold does not provide clinically noticeable results in canine patients.

کلیدواژه ها:

Canine teeth ، Bone marrow derived stem cells ، Pulp/dentin regeneration ، Vital pulp therapy

نویسندگان

Saeed Farzad-Mohajeri

Institute of Biomedical Research, University of Tehran, Tehran, Iran.

Mirsepehr Pedram

Depatment of Surgery and Radiology, Faculty of veterinary medicine, University of Tehran

Nasrin Saeedifar

School of Dentistry, International Campus of Tehran University of Medical Sciences, Tehran, Iran.

Fatemeh Mashhadi-Abbas

Department of Oral and Maxillofacial Pathology, Shahid Beheshti University of medical Sciences, Tehran, Iran

Mohammad Dehghan

Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

Naghmeh Bahrami

Craniomaxillofacial Research center, Tehran University of Medical Sciences, Tehran, Iran

Sedighe Sadat Hashemi Kamangar

Department of Operative Dentistry, International Campus, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Clarke DE. Vital pulp therapy for complicated crown fracture of ...
  • Holmstrom SE. Veterinary dentistry: A team approach. ۲nd Missouri, USA: ...
  • Hale FA. Dental caries in the dog. Can Vet J ...
  • Trope M. The expanding role of vital pulp therapy. Dent ...
  • Bergenholtz G, Axelsson S, Davidson T, et al. Treatment of ...
  • Bjørndal L, Demant S, Dabelsteen S. Depth and activity of ...
  • Khalil IT, Sarkis T, Naaman A. MM-MTA for direct pulp ...
  • Komabayashi T, Zhu Q. Innovative endodontic therapy for anti-inflammatory direct ...
  • Bjørndal L, Mjör IA. Pulp-dentin biology in restorative dentistry. Part ...
  • Kamal EM, Nabih SM, Obeid RF, et al. The reparative ...
  • Simon S, Cooper P, Smith A, et al. Evaluation of ...
  • Torabinejad M, Hong CU, McDonald F, et al. Physical and ...
  • Lipski M, Nowicka A, Kot K, et al. Factors affecting ...
  • Schmitt D, Lee J, Bogen G. Multifaceted use of ProRoot ...
  • Kato C, Suzuki M, Shinkai K, et al. Histopathological and ...
  • Briso AL, Rahal V, Mestrener SR, et al. Biological response ...
  • Gong W, Huang Z, Dong Y, et al. Ionic extraction ...
  • Tran XV, Gorin C, Willig C, et al. Effect of ...
  • Al-Saudi KW, Nabih SM, Farghaly AM, et al. Pulpal repair ...
  • Dammaschke T, Nowicka A, Lipski M, et al. Histological evaluation ...
  • Obeid M, Saber Sel D, Ismael Ael D, et al. ...
  • Abdelaz P, ElZoghbi A, Shokry M, et al. Reparative dentin ...
  • Sharma S, Srivastava D, Grover S, et al. Biomaterials in ...
  • Wahl DA, Sachlos E, Liu C, et al. Controlling the ...
  • Smith JA, van den Broek FA, Martorell JC, et al. ...
  • Bahrami N, Malekolkottab F, Ebrahimi-Barough S, et al. The effect ...
  • Eskandarizadeh A, Parirokh M, Eslami B, et al. A comparative ...
  • Faraco Junior IM, Holland R. Histomorphological response of dogs’ dental ...
  • Dominguez MS, Witherspoon DE, Gutmann JL, et al. Histological and ...
  • Bidar M, Naghavi N, Mohtasham N, et al. Mineral trioxide ...
  • Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM, et al. Fusion of ...
  • Gronthos S, Mankani M, Brahim J, et al. Postnatal human ...
  • Seo BM, Miura M, Gronthos S, et al. Investigation of ...
  • Huang AH, Snyder BR, Cheng PH, et al. Putative dental ...
  • Zhou J, Shi S, Shi Y, et al. Role of ...
  • Nadri S, Soleimani M, Hosseni RH, et al. An efficient ...
  • Pertoft H. Fractionation of cells and subcellular particles with Percoll. ...
  • Jaiswal N, Haynesworth SE, Caplan AI, et al. Osteogenic differentiation ...
  • Li ZY, Chen L, Liu L, et al. Odontogenic potential ...
  • Frozoni M, Marques MR, Hamasaki SK, et al. Contribution of ...
  • Saraswathi P, Saravanakumar S. A simple method of tooth regeneration ...
  • Tziafas D, Smith AJ, Lesot H. Designing new treatment strategies ...
  • Frozoni M, Zaia AA, Line SR, et al. Analysis of ...
  • Frozoni M, Marques MR, Gilioli R, et al. Required time ...
  • Xu W, Jiang S, Chen Q, et al. Systemically transplanted ...
  • Chamberlain G, Fox J, Ashton B, et al. Concise review: ...
  • Das R, Jahr H, van Osch GJ, et al. The ...
  • Keklikoglu N, Akinci S. Comparison of three different techniques for ...
  • Rashed F. A comparative study of the dentition and temporomandibular ...
    • نمایش کامل مراجع