ورود
مقالات فارسیISIکنفرانسهاژورنالها

Echocardiographic assessment of intravenous administration of medetomidine and xylazine hydrochloride at different sedative doses in one-humped camel calves (Camelus dromedarious)

محل انتشار: گفتمان پژوهش دامپزشکی، دوره: 13، شماره: 1
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 52

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https://civilica.com/doc/1818749

شناسه ملی سند علمی:

JR_VRFAN-13-1_006

تاریخ نمایه سازی: 25 آبان 1402

چکیده مقاله:

Echocardiography illustrates a convenient and noninvasive tool for measuring cardiac output (CO) changes after administration of sedative drugs, but it is unknown in camelids practice. The aim of present study was to investigate echocardiographic effects of intravenous (IV) injection of medetomidine and xylazine in camel calves. Twenty apparently healthy immature male one-humped camel calves (Camelus dromedarious) were divided into four groups (five animals in each treatment). Medetomidine and xylazine were injected into the left jugular vein at two different doses of ۱۰.۰۰ and ۲۰.۰۰ μg kg-۱ and ۰.۲۰ and ۰.۴۰ mg kg-۱, respectively. Effects on some selected echocardiographic parameters were recorded at different intervals, before drug administrations (baseline) and after ۳, ۶۰ and ۱۲۰ min. Data were analyzed by repeated measure, ANOVA test, then relevance and significance were taken as p ≤ ۰.۰۵. Significant decrease in fractional shortening percentage (FS%), ejection fraction percentage (EF%), stroke volume (SV), heart rate (HR) and subsequent CO were noticeable ۳ min after drug administration in medetomidine high dose (MH), medetomidine low dose (ML) and xylazine high dose (XH) groups (p ≤ ۰.۰۵), furthermore at this time significant decrease in left ventricular mass (LVmass) and left ventricular systolic time intervals were seen in these groups, however, in xylazine low dose (XL) group, the lowest level of most echocardiographic parameters were detectable after ۶۰ min. High dose IV injection of medetomidine was associated with significant decrease in most echocardiographic parameters without echocardiographic arrhythmia. Although, ML and XH groups had the same effects on echocardiographic indices but the intensity and duration were less than MH group.

کلیدواژه ها:

α۲-adrenoceptor agonist drugs ، Dromedary camel ، Echocardiography ، Medetomidine ، Xylazine

نویسندگان

Mohammad Reza Esmaili Nejad

Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

Majid Masoudifard

Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

Omid Azari

Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran

Ehsanollah Sakhaee

Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran

Nima Ghalekhani

HIV/STI Surveillance Research Center, WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran

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  • England GC, Clarke KW. Alpha ۲ adrenoreceptor agonists in the ...
  • Kinjavdekar P, Singh Amarpal GR, Aithal HP, et al. Physiologic ...
  • Al-Mubarak AI, Abdin-Bey M, Ramadan RO. A retrospective clinical evaluation ...
  • Cruz JI, Loste JM, Burzaco OH. Observations on the use ...
  • Scheinin M, MacDonald E. An introduction to the pharmacology of ...
  • Dugdale A. Veterinary anesthesia: Principles to practice. Oxford, UK: Willey-Blackwell, ...
  • Pypendop BH, Verstegen JP. Hemodynamic effects of medetomidine in the ...
  • Murrell JC, Hellebrekers LJ. Medetomidine and dexmedetomidine: a review of ...
  • Paddleford RR, Harvey RC. Alpha ۲ Agonists and antagonists. Vet ...
  • Dart CM. Advantages and disadvantages of using alpha-۲ agonists in ...
  • Thomas WP, Gaber CE, Jacobs GJ, et al. Recommendations for ...
  • Reef VB. Echocardiographic examination in the horse: the basics. Compend ...
  • Hallowell GD, Potter TJ, Bowen IM. Methods and normal values ...
  • Buczinski S. Cardiovascular ultrasonography in cattle. Vet Clin North Am: ...
  • McConachie E, Barton MH, Rapoport G, et al. Doppler and ...
  • Tibby SM, Murdoch IA. Measurement of cardiac output and tissue ...
  • Braun U, Schweizer Determination of heart dimensions in cattle via ...
  • Zarifi M, Buczinski S, Rezakhani A, et al. Effect of ...
  • Tharwat M, Al-Sobayil F, Ali A, et al. Echocardiography of ...
  • Al-Taher AY, Zabady MK, Almubarak A, et al. Clinical use ...
  • Wagner AE, Muir WW ۳rd, Hinchcliff KW. Cardiovascular effects of ...
  • Maze M, Tranquilli W. Alpha-۲ adrenoceptor agonists: defining the role ...
  • Masoudifard M, Esmailinejad MR, Sakhaee E, et al. Pulsed wave ...
  • Sinclair MD. A review of the physiological effects of alpha۲-agonists ...
  • Bueno AC, Cornick-Seahorn J, Seahorn TL, et al. Cardiopulmonary and ...
  • Marcilla M, Schauvliege S, Duchateau L, et al. Cardiopulmonary effects ...
  • Bettschart-Wolfensberger R, Kalchofner K, Neges K, et al. Total intravenous ...
  • Bryant CE, Clarke KW, Thompson J. Cardiopulmonary effects of medetomidine ...
  • Devereux RB, Alonso DR, Lutas EM, et al. Echocardiographic assessment ...
  • Markus MR, Freitas HF, Chizzola PR, et al. Left ventricular ...
  • Sousa MG, Carareto R, De-Nardi AB, et al. Effects of ...
  • Saponaro V, Crovace A, De Marzo L, et al. Echocardiographic ...
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