Identification of bovine leukemia virus in raw milk samples in North-West of Iran

سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 63

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شناسه ملی سند علمی:

JR_VRFAN-12-2_013

تاریخ نمایه سازی: 27 آبان 1402

چکیده مقاله:

Bovine leukemiavirus (BLV) is one of the most important carcinogenic viruses genetically related to the human T-cell lymphotropic viruses (HTLV-۱ and HTLV-۲). The virus infects type B lymphocytes and creates lymph glands tumors. Recently, the association between the presence of this virus and breast cancer has been addressed in humans. Here, we studied the prevalence of BLV in the samples of raw milk of native Iranian and Iranian-foreign cows in traditional, semi-industrial and industrial dairy farms in rural and urban areas of Zanjan province. Raw milk samples of cows were collected manually in sterile tubes. The samples were tested by nested-PCR method. Forty samples (۹.۹۳%) out of ۴۰۳ samples showed BLV contamination. In this study, nested-PCR was successfully applied to determine the level of contamination in raw milk samples from cows infected with BLV. Furthermore, a relatively high rate of BLV infection was found in dairy cows in Zanjan province, northwestern of Iran.

نویسندگان

Hossein Barzeghar

Department of Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

Hessam Mirshahabi

Department of Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

Nima Motamed

Department of Social Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

Massoud Yavarmanesh

Department of Food science and Technology, Ferdowsi University of Mashhad, Mashhad, Iran

Behroz Mahdavi Poor

Department of Laboratory Sciences, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran

Seyyed Reza Moaddab

Department of Laboratory Sciences, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran

Mohammad Asgharzadeh

Hematology and Oncology Research Center, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran

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