Anti-Rh۱۷ Alloimmunization: A Rare Case of Severe Hemolytic Disease of the Newborn and Review of the Literature

سال انتشار: 1398
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 57

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شناسه ملی سند علمی:

JR_JPRE-8-1_004

تاریخ نمایه سازی: 9 آذر 1402

چکیده مقاله:

Background: ABO/Rh incompatibilities are common causes of hemolytic disease of newborn. Alloimmunization due to minor RBC antigens may also cause severe hemolysis and hyperbilirubinemia necessitating exchange transfusion in the early neonatal period. Case Presentation: Here we report a rare case (first such report to our knowledge in Iran) of severe hemolytic disease of the newborn due to anti-Rh۱۷ antibody (an antibody to the RhCc/Ee antigen protein) in a newborn with maternal blood group B Rh D--. Conclusion: Presenting this case would improve the insight and knowledge about managing severe hemolytic anemia due to minor group alloantibodies postnatally, and highlight the importance of prenatal surveillance and diagnosis for the optimal management of alloimmune hemolytic disease.

نویسندگان

Farhad Abolhassan Choobdar

Department of Neonatology, Aliasghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.

Hani Milani

Department of Neonatology, Kamali Hospital, Alborz University of Medical Sciences, Karaj, Iran.

Kamran Behrouzi

Department of Neonatology, Kamali Hospital, Alborz University of Medical Sciences, Karaj, Iran.

Nasrin Khalesi

Department of Neonatology, Aliasghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.

Behzad Haghighi

Department of Pediatric Intensive Care, Aliasghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.

Ali Manafi

Department of Pediatric Intensive Care, Aliasghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.

Mohammad Naderisorki

Thalassemia Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Sorraya Shojaee

Department of Neonatology, Aliasghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.

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