A new record of Scedosporium dehoogii isolated from paddy field soil in Iran: Phylogeny and antifungal susceptibility profiles
محل انتشار: سرطان معده، دوره: 8، شماره: 4
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 64
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شناسه ملی سند علمی:
JR_CUMM-8-4_005
تاریخ نمایه سازی: 11 آذر 1402
چکیده مقاله:
Background and Purpose: Scedosporium species are ubiquitous environmental fungi,which are considered emerging agents that trigger disease in humans and animals. Thepresent study aimed to determine Scedosporium dehoogii strain isolated from paddy field soil samples using semi-selective media and evaluate its antifungal susceptibility profile.Materials and Methods: Three paddy field soil samples were collected during aninvestigation for the isolation of Scedosporium species in Mazandaran province, Iran.Morphological and molecular analyses based on ITS-rDNA sequencing were performed. Furthermore, in vitro antifungal susceptibility testing for conventional drugs and novel imidazole (luliconazole) was performed based on Clinical and Laboratory Standards Institute M۳۸-A۳ guidelines.Results: In this study, S. dehoogii was isolated from the soil in paddy fields. Based onthe results, itraconazole and luliconazole showed the least and most antifungal activityagainst this isolate, respectively.Conclusion: Based on the findings, molecular identification was essential fordistinguishing the species of S. dehoogii. Remarkably, luliconazole showed potent activity against this strain.
کلیدواژه ها:
نویسندگان
Javad Javidnia
Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Hamid Badali
Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Jalal Jafarzadeh
Department of Medical Parasitology and Mycology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
Iman Haghani
Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Mahdi Abastabar
Department of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
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