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Proven pulmonary aspergillosis in a COVID-۱۹ patient: A case report

محل انتشار: سرطان معده، دوره: 7، شماره: 2
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 45

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استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1838075

شناسه ملی سند علمی:

JR_CUMM-7-2_007

تاریخ نمایه سازی: 11 آذر 1402

چکیده مقاله:

Background and Purpose: Coronavirus disease ۲۰۱۹ (COVID-۱۹) has become a significant clinical challenge in healthcare settings all over the world. Critically ill COVID-۱۹ patients with acute respiratory distress syndrome may be at increased risk of co-infection with pulmonary aspergillosis. This study aimed to describe a clinical case of proven pulmonary aspergillosis caused by Aspergillus tubingensis in a ۵۹-year-old man with a history of hospitalization due to COVID-۱۹ infection.Case report: The Covid-۱۹ infection was confirmed by positive nasopharyngeal polymerase chain reaction. He had a cavitary lesion measured ۲۰ mm in diameter with intracavitary soft tissue density in the left lung in the first chest computerized tomography scan. After ۲۵ days, he showed two cavitary lesions in both lungs which raised suspicion of fungal infection; hence, the patient underwent a trans-thoracic biopsy of the cavitary lesion. The direct examination and culture of the biopsy material revealed Aspergillus species. To confirm the Aspergillus species identification, the beta-tubulin region was sequenced. The patient was treated with oral voriconazole.Conclusion: This report underlined the importance of early diagnosis and management of invasive fungal infections in severe COVID-۱۹ patients

کلیدواژه ها:

Aspergillosis ، Aspergillus tubingensis ، COVID-۱۹

نویسندگان

Mohammadreza Salehi

Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Sadegh Khodavaisy

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Nasim Khajavirad

Department of Internal Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Alireza Izadi

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Seyed Ali Dehghan Manshadi

Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Alireza Abdollahi

Department of Pathology, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Tehran, Iran

Amir Aliramezani

Central Laboratory, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Tehran, Iran

Elahe Sasani

Department of Mycology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

Mahsa Abdorahimi

Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran

Reyhaneh Sadat Kiyaeie

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Zohre Khosravany

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Muhammad Getso

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Department of Medical Microbiology and Parasitology, College of Health Sciences, Faculty of Clinical Sciences,

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