ورود
مقالات فارسیISIکنفرانسهاژورنالها

Chemical compositions and antifungal activities of Satureja macrosiphon against Candida and Aspergillus species

محل انتشار: سرطان معده، دوره: 5، شماره: 4
سال انتشار: 1398
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 67

فایل این مقاله در 6 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1838087

شناسه ملی سند علمی:

JR_CUMM-5-4_004

تاریخ نمایه سازی: 11 آذر 1402

چکیده مقاله:

Background and Purpose: Despite the various applications of Satureja species, there are limited data in this domain. Regarding this, the present study was conducted to investigate the essential oil (EO) biological activity of S. macrosiphon species in Iran. Materials and Methods: The EO of S. macrosiphon flowers was obtained by hydrodistillation. Chemical compositions of the EO were analyzed using gas chromatography-mass spectrometry. In addition, minimum inhibitory concentrations (MIC) were measured by means of the broth microdilution method. The estimation of antibiofilm and cytotoxic activities was also accomplished using the tetrazolium salt and MTT assays, respectively. Results: A total of ۲۶ components were identified in the EO with linalool as the main constituent (۲۸.۴۶%). A MIC range value of ۰.۲۵-۸ μL/mL was obtained against all of the tested fungi. The EO inhibited the biofilm development of the Candida tested strains at a concentration of ۴-۸ μL/mL. Cytotoxicity (IC۵۰) of EO against the HeLa cell was greater than the MIC concentration (۶.۴۹ μL/mL). Conclusion: Based on the findings, it was concluded that the EO of S. macrosiphon has the potential for further use as an antifungal agent.

کلیدواژه ها:

Essential oil ، MTT assay ، Satureja macrosiphon ، XTT assay

نویسندگان

Marjan Motamedi Motamedi

Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Mohammad Jamal Saharkhiz

Department of Horticultural Sciences, Faculty of Agriculture, Shiraz University, Shiraz, Iran

Keyvan Pakshir

Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Sara Amini Akbarabadi

Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Marzieh Alikhani Khordshami

Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Fatemeh Asadian

Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Zahra Zareshahrabadi

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Kamiar Zomorodian

Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Vazquez JA, Miceli MH, Alangaden G. Invasive fungal infections in ...
  • Person AK, Kontoyiannis DP, Alexander BD. Fungal infections in transplant ...
  • Mousset S, Buchheidt D, Heinz W, Ruhnke M, Cornely OA, ...
  • Badiee P, Hashemizadeh Z. Opportunistic invasive fungal infections: diagnosis & ...
  • Bongomin F, Gago S, Oladele RO, Denning DW. Global and ...
  • Caston-Osorio J, Rivero A, Torre-Cisneros J. Epidemiology of invasive fungal ...
  • Lehrnbecher T, Frank C, Engels K, Kriener S, Groll AH, ...
  • Jarvis WR. Epidemiology of nosocomial fungal infections, with emphasis on ...
  • Perlroth J, Choi B, Spellberg B. Nosocomial fungal infections: epidemiology, ...
  • Jantunen E, Anttila VJ, Ruutu T. Aspergillus infections inallogeneic stem ...
  • Patterson TF, Kirkpatrick WR, White M, Hiemenz JW, Wingard JR, ...
  • Sanglard D. Emerging threats in antifungal-resistant fungal pathogens. Front Med. ...
  • Dannaoui E, Desnos-Ollivier M, Garcia-Hermoso D, Grenouillet F, Cassaing S, ...
  • Jensen RH, Johansen HK, Arendrup MC. Stepwise development of a ...
  • Riat A, Plojoux J, Gindro K, Schrenzel J, Sanglard D. ...
  • Breda CA, Gasperini AM, Garcia VL, Monteiro KM, Bataglion GA, ...
  • El-Khateeb AY, Elsherbiny E, Tadros L, Ali S, Hamed H. ...
  • Patel P, Patel N, Patel D, Desai SH, Meshram D. ...
  • Azaz AD, Kürkcüoglu M, Satil F, Can Baser KH, Tümen ...
  • Zeidan-Chulia F, Keskin M, Kononen E, Uitto VJ, Soderling E, ...
  • Farzaneh M, Kiani H, Sharifi R, Reisi M, Hadian J. ...
  • Bezic N, Dunkic V, Elma V. Antiphytoviral activity of essential ...
  • Bagheri S, Ahmadvand H, Khosrowbeygi A, Ghazanfari F, Jafari N, ...
  • Adams RP. Identification of essential oil components by gas chromatography/mass ...
  • Alastruey-Izquierdo A, Melhem MS, Bonfietti LX, Rodriguez-Tudela JL. Susceptibility test ...
  • Sabaeifard P, Abdi-Ali A, Soudi MR, Dinarvand R. Optimization of ...
  • Riss TL, Moravec RA, Niles AL, Duellman S, Benink HA, ...
  • Saharkhiz MJ, Zomorodian K, Taban A, Pakshir K, Heshmati K, ...
  • Amiri H. The in vitro antioxidative properties of the essential ...
  • Trombetta D, Castelli F, Sarpietro MG, Venuti V, Cristani M, ...
  • Kundakovic T, Stanojkovic T, Kolundzija B, Markovic S, Sukilovic B, ...
  • Bukvicki D, Stojkovic D, Sokovic M, Vannini L, Montanari C, ...
  • Gorran A, Salehnia B, Farzaneh HR, Farzaneh M, Shivazad M. ...
  • Slavkovska V, Jancic R, Bojovic S, Milosavljevic S, Djokovic D. ...
  • Kremer D, Kosir IJ, Koncic MZ, Cerenak A, Potocnik T, ...
  • Park M, Gwak K, Yang I, Kim K, Jeung E, ...
  • Cha JD, Jung EK, Kil BS, Lee KY. Chemical composition ...
  • Alviano W, Mendonca‐Filho R, Alviano D, Bizzo H, Souto‐Padron T, ...
  • Ramage G, Rajendran R, Sherry L, Williams C. Fungal biofilm ...
  • Manoharan RK, Lee JH, Kim YG, Kim SI, Lee J. ...
    • نمایش کامل مراجع