Catheter-Directed Thrombolysis for Acute SVC Obstruction in a Patient with Metastatic Breast Cancer
محل انتشار: فصلنامه سرطان پستان، دوره: 9، شماره: 3
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 40
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شناسه ملی سند علمی:
JR_ARCHB-9-3_013
تاریخ نمایه سازی: 14 آذر 1402
چکیده مقاله:
Background: External compression, thrombosis, or stenosis of the superior vena cava can lead to superior vena cava syndrome, a diagnosis that should be considered swiftly in patients presenting with classic symptoms such as facial and neck swelling, plethora, and distended neck veins.
Case Presentation: We report a case of acute port-a-cath associated superior vena cava thrombosis in a longstanding, previously uncomplicated vascular access device in a patient with stable ER+/PR+/HER۲+ metastatic breast cancer. After initial treatment, there was limited clinical improvement with subcutaneous low molecular weight heparin (LMWH). Following multidisciplinary team discussion, catheter-directed thrombolysis was performed, which resulted in complete symptom resolution.
Conclusion: The recognition of signs and symptoms is crucial in diagnosing acute superior vena cava syndrome, particularly in patients with a malignancy history or a central venous access device in situ. The thrombotic complications of port-a-cath symptoms can occur at any time and management should be guided by multidisciplinary discussion. In appropriately selected patients, catheter-directed thrombolysis can be successful and can lead to rapid symptom resolution.
کلیدواژه ها:
نویسندگان
Hailey Kathryn Carrol
Department of Medical Oncology, Cork University Hospital, Wilton, Cork, Ireland
Fergal Dineen
Department of Medical Oncology, Cork University Hospital, Wilton, Cork, Ireland
Paul Ryan
Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland
Maeve P Crowley
Comprehensive Coagulation Centre, Cork University Hospital, Wilton, Cork, Ireland