Steroid Compounds from Endophytic (Penicillium sp.) of Mangrove Avicennia marina

Syaiful Bahri; Annisa Elcentia Fajarwati; Andi Setiawan; John Hendri; Suripto Dwi Yuwono; Yuli Ambarwati; Rahadian Zainul

Steroid Compounds from Endophytic (Penicillium sp.) of Mangrove Avicennia marina

محل انتشار: مجله علوم دارویی و شیمی، دوره: 7، شماره: 2

سال انتشار: 1403

نوع سند: مقاله ژورنالی

زبان: انگلیسی

مشاهده: 51

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لینک ثابت به این مقاله:

https://civilica.com/doc/1845075

شناسه ملی سند علمی:

JR_JMCH-7-2_012

تاریخ نمایه سازی: 15 آذر 1402

چکیده مقاله:

In this study, we explore a steroid compound from the endophytic of the mangrove (Avicennia marina). Penicillium sp. is one of the microbes endophytic isolated from the mangrove and induced in the chitin medium by the so-called "cultivation". The cultivation in the medium is a strategy to enhance secondary metabolites production. In addition, the steroid compound of the secondary metabolites can be extracted and isolated from the purified fraction, followed by analysis and characterization to validate the target compound. Using the acquired ۱۴MA۱۵ fraction as a representative sample, we found that it presents a peak in the UV spectrum at a wavelength of ۲۰۶ nm from the carbonyl group. The stretching vibration of C=O group in the IR spectrum is also confirmed at ۱۷۱۲ cm-۱. Furthermore, other stretching vibrations from the O-H group, C-O group, and –C–H group are detected at ۳۴۱۰ cm-۱, ۱۰۵۵ cm-۱, and ۱۴۶۳ - ۷۲۳ cm-۱, respectively. Therefore, it is concluded that the steroid compound proposed has a molecular formula of C۲۶H۴۰O۲ according to MS fragmentation analysis.

کلیدواژه ها:

antibacterial ، Avicennia marina ، endophytic ، Penicillium sp ، Steroid

نویسندگان

Syaiful Bahri