Comparative HPLC Analysis of ۶-Gingerol and ۶-Shogaol in Soil-Based and Soilless-Grown Ginger

سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 72

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شناسه ملی سند علمی:

JR_JJMPB-12-4_002

تاریخ نمایه سازی: 26 آذر 1402

چکیده مقاله:

Ginger or Zingiber officinale Roscoe is a well-known herbal medicine and is widely used in Asian cuisine. Its major bioactive compounds, ۶-gingerol and its dehydrated form, ۶-shogaol, were reported to have potential medicinal properties. However, previous phytochemical studies on the compounds are limited to conventionally grown or soil-based ginger, neglecting soilless ginger grown through hydroponic techniques. This technique has been widely adopted as an alternative to circumvent soil-related complications. Therefore, this study aimed to compare both marker compounds in soil-based (SB) and soilless-grown hydroponic (HP) ginger extracted in different ethanol concentrations (۹۵% and ۱۰۰%) using high-performance liquid chromatography. The study initially found that ۶-gingerol concentration in ۹۵% SB ginger ethanolic extract (۱.۰۱۲%) was significantly higher (p<۰.۰۵) than in ۹۵% HP dried ginger (HP۱) ethanolic extract (۰.۳۱۴%). The ۶-gingerol content for both gingers were also significantly higher (p<۰.۰۵) in ۹۵% ethanolic extracts compared to ۱۰۰% ethanolic extracts. The analysis was also performed with fresh-dried HP ginger (HP۲), and it was found that the HP۲ ginger (۰.۷۵%) has a significantly higher ۶-gingerol concentration (p<۰.۰۵) compared to HP۱ ginger (۰.۳۱۴%), confirming that the previous results were implicated by storage conditions. The concentration of ۶-gingerol in ۹۵% SB ginger extract (۱.۰۱۲%) differ significantly compared to those in HP۲ extract (۰.۷۵%) while both gingers have equivalent amount of low ۶-shogaol concentrations (۰.۰۰۰۴% and ۰.۰۰۰۵% respectively). It is worth to note that HP ginger grown in soilless condition could still produce high amount of ۶-gingerol. This finding encourages the usage of HP ginger in pharmacological studies considering the other economic and environmental benefits it offers.

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نویسندگان

Liyana Shafiqah Sahul Hamid

Centre for Drug and Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Juriyati Jalil

Centre for Drug and Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Syahira Mohd. Abdul Wahab

Centre for Drug and Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Norazrina Azmi

Centre for Drug and Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Nor Syafinaz Yaakob

Centre for Drug and Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

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