Molecular and Physiological Study in Patients with Coronavirus in Thi-Qar Province Iraq

The current study aimed to study the effect of Covid-۱۹ disease on some physiological parameters for assessing the physiological effect of Covid-۱۹. The current study included ۱۰۰ patients, ۵۰ males, and ۵۰ females, whose ages ranged from ۱۰ – ۷۳ years infected with Covid-۱۹ molecularly diagnosed at AL-Imam Hussein Teaching Hospital in Thi-Qar Province from April to August ۲۰۲۱ and ۵۰ people as a control group. The results illustrated a significant decrease in the level of hemoglobin, lymphocyte, and platelet in the patient's group, whereas a significant increase in the count of total white blood cells (WBC) was recorded in patients compared with the control group. The results showed that the hemoglobin level, WBC, and platelet increased significantly in males compared to females, while the lymphocytes increased significantly in female patients. The results of age groups showed non-significant differences in the hematological parameters. The current results illustrated a significant increase in the level of blood urea, serum creatinine, and random blood sugar in the patient's group. According to the gender of patients, the blood urea increased significantly in the female group, while the blood sugar increased significantly in the male group. On the other hand, the serum creatinine had no significant difference. According to age groups, a significant increase in blood urea was recorded in patients over ۷۰ years, but no differences in both creatinine and random blood sugar level were noted. The current study recorded that the concentration of CRP, ferritin, and D. Dimer was significantly higher in patients; according to gender, the level of CRP and ferritin increased non-significantly compared with a male group of patients, while D. Dimer increased significantly in the female group. According to age group, only CRP increased significantly in the first age group compared with other age groups. The sequencing analysis was performed for ۱۰ isolated Covid-۱۹, and the result indicates that only one isolated sample has a sequencing identity of ۹۹,۵% with Covid-۱۹ in Iran.