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مقالات فارسیISIکنفرانسهاژورنالها

Evaluation of Immunogenicity of Clostridium perfringens Type B Toxoid and Inactivated FMD (O) Virus with Adjuvant (ISA۷۰-MF۵۹)

محل انتشار: مجله آرشیو رازی، دوره: 78، شماره: 3
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 61

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لینک ثابت به این مقاله:
https://civilica.com/doc/1867621

شناسه ملی سند علمی:

JR_ARCHRAZI-78-3_014

تاریخ نمایه سازی: 6 دی 1402

چکیده مقاله:

Foot and mouth disease (FMD) and enterotoxemia are important diseases of hoofed animals. Vaccination against livestock pathogens, especially these two diseases, plays a key role in the prevention and control of these diseases. The use of combined vaccines with the aim of creating a better immune response and producing cheaper vaccines is a great contribution to Vaccine industry. This research aimed to compare the immunogenicity of FMD (O) and Clostridium perfringens type B toxoid along with adjuvant (MF۵۹) and Montanide (ISA۷۰) to create the best immunogenicity. To investigate the immune responses of vaccines, it was injected into an animal model, and the antibody titer was measured by enzyme-linked immunosorbent assay (ELISA) test and VN antibody titer. The results showed that the formulation with MF۵۹ adjuvant brought more stable immunogenicity against FMD and Clostridium perfringens type B, and the length of the immunogenicity period also increased significantly. Therefore, the combined vaccine (Clostridium perfringens + FMD) could play a major role invaccine industry as an alternative vaccine against Clostridium perfringens and FMD in livestock.

کلیدواژه ها:

Clostridium perfringens ، combination vaccine ، FMD ، ISA۷۰ ، MF۵۹

نویسندگان

A Araghi

Department of Microbiology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

M Taghizadeh

Department of Research and Development, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran

S. R Hosseini Doust

Department of Microbiology, Faculty of Advanced Sciences, Islamic Azad University Tehran Medical Sciences, Tehran, Iran

A Paradise

Department of Anaerobic Vaccine Research and Production, Specialized Clostridia Research Laboratory, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran

S. M Azimi Dezfouli

Department of Foot and Mouth Vaccine Production, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran

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  • Spickler AR, Roth JA. Adjuvants in veterinary vaccines: modes of ...
  • Tizard IR. Adjuvants and adjuvanticity. In: Tizard IR, editor. Vaccines ...
  • Ohtani K, Shimizu T. Regulation of Toxin Production in Clostridium ...
  • Pilehchian Langroudi R, Jabbari A, Moosawi Shoshtary M, Pardis A. ...
  • Khorasani A, Madadgar O, Soleimanjahi H, Keyvanfar H, Mahravani H. ...
  • Zaragoza NE, Orellana CA, Moonen GA, Moutafis G, Marcellin E. ...
  • Zayerzadeh E, Fardipour A, Jabbari AR. A new purification method ...
  • Ardehali M, Darakhshan H. Role of alum as adjuvant in ...
  • Bradford MM. A rapid and sensitive method for the quantitation ...
  • Fathi Najafi M, Mashhadi M, Hemmaty M. Effectiveness of Chitosan ...
  • Mahravani H. Evaluation of Foot and Mouth Disease virus concentration ...
  • Gray AR, Wood BA, Henry E, Azhar M, King DP, ...
  • Tahir MF, Mahmood MS, Hussain I. Preparation and comparative evaluation ...
  • Paradise A, Abdolmohammadi Khiav L. Evaluation of epsilon antitoxin of ...
  • Grubman MJ, Baxt B. Foot-and-mouth disease. Clin Microbiol Rev. ۲۰۰۴;۱۷(۲):۴۶۵-۹۳ ...
  • Rweyemamu MM, Booth JC, Parry N, Pay TW. Neutralization kinetics ...
  • El-Bagoury G, El-Habbaa A, Gamil M, Fawzy H. Evaluation of ...
  • Lindblad EB, Duroux L. Mineral Adjuvants∗∗The present chapter is an ...
  • Yamanaka M, Okabe T, Nakai M, Goto N. Local pathological ...
  • Ou H, Yao H, Yao W, Wu N, Wu X, ...
  • Tariq M, Anjum AA, Sheikh AA, Awan AR, Ali MA, ...
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