Antibiotic Resistance Profile and Multiple Antibiotic Resistance Index of Campylobacter Species Isolated from Poultry
محل انتشار: مجله آرشیو رازی، دوره: 76، شماره: 6
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 47
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شناسه ملی سند علمی:
JR_ARCHRAZI-76-6_012
تاریخ نمایه سازی: 6 دی 1402
چکیده مقاله:
Campylobacter is a major public health problem, leading to foodborne diarrhea in the world. The current study aimed to isolate Campylobacter in different sources of poultry and determine antimicrobial susceptibility. A total of ۱۵۰ fecal and ۲۹ cloacal swabs were obtained from poultry farms (۸۴ cloacal swabs) and live bird markets (LBMs), respectively, and ۳۷ cecal swabs were also acquired from a local slaughterhouse located in the middle Euphrates region. Campylobacter Species (spp.) was first isolated and characterized by conventional bacteriological methods. Secondly, the antimicrobial susceptibility of isolates was investigated by disc diffusion method. The overall prevalence of Campylobacter spp. isolated from fecal cloacal and cecal poultry samples was ۲۴% (۳۶ out of ۱۵۰). All strains were resistant to Nalidixic acid and Ciprofloxacin (۱۰۰%), with high resistance to Tetracycline (۸۸.۸%), Ampicillin (۸۳.۳%), Sulpha/Trimethoprim (۸۰.۵%), Erythromycin (۵۰%), and Ceftriaxone (۵۰%), but less resistant to Gentamicin (۳۰.۵%), Amoxi-Clav (۲۷.۷%), and Chloramphenicol (۲۲.۲%). The majority of isolates (۹۷.۲%) scored a multiple antibiotic resistance (MAR) index of ۰.۳ or more, and ۳۵ (۹۷.۲%) isolates were resistant to three or more antibiotic classes. Particularly, ۶۱.۱% of the isolates were multidrug resistance (MDR), ۳۶.۱% of the isolates were extensively drug resistant, and ۲.۸% of the isolates were Pan drug resistant. Moreover, the current study detected ۲۴ multiple resistance patterns from ۳۶ isolates of Campylobacter spp., and most of the isolates (۲۷ out of ۳۶) displayed an important route of resistance to Nalidixic acid, Ciprofloxacin, and Tetracycline. Based on the results, increased resistance rates to commonly used antibiotics in Campylobacter were recovered from poultry farms, LBMs, and local slaughterhouses. The majority of strains were MDR to commonly used antimicrobials with elevated MAR indices, requiring implementation of a national strategy to improve husbandry practice and the effective use of antibacterial agents, alternatives, and vaccines.
کلیدواژه ها:
نویسندگان
Z. M Shakir
Heath Department, National Center for Occupational Health and Safety, AL-Najaf Governorate, Iraq
A. O Alhatami
Department of Public Health, Faculty of Veterinary Medicine, University of Kufa, Kufa, Iraq
Y Ismail Khudhair
Department of Internal and Preventive Medicine, College of Veterinary Medicine, University of Al-Qadisiyah, Al-Diwaniyah, Iraq
H Muhsen Abdulwahab
Department of Pathology and Poultry Diseases, Faculty of Veterinary Medicine, University of Kufa, Kufa, Iraq
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