ورود
مقالات فارسیISIکنفرانسهاژورنالها

Chitosan-based Nanoparticles in Mucosal Vaccine Delivery

محل انتشار: مجله آرشیو رازی، دوره: 73، شماره: 3
سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 43

فایل این مقاله در 12 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1868679

شناسه ملی سند علمی:

JR_ARCHRAZI-73-3_001

تاریخ نمایه سازی: 6 دی 1402

چکیده مقاله:

Most infectious diseases are caused by pathogenic infiltrations from the mucosal tract. Nowadays, the use of vaccines has been widely investigated for the prevention of different infectious diseases, infertility, immune disorders, malignancies, and allergies. Broad-spectrum adjuvant substances have been studied for immune system stimulation with a greater efficiency against specific antigens. Various adjuvants have been developed such as inorganic, oil-based, and emulsion adjuvants, bacterial products and their derivatives, cytokines, cytosine-guanine dinucleotide (CpG) motifs, and particulate systems. Mucosal vaccine delivery is an alternative route to induce both humoral and cellular immune responses. Applying nanoparticles in vaccine formulations allows not only improved antigen stability and immunogenicity, but also targeted delivery, and consequently, more specific release of the agent of interest. Chitosan nanoparticles have immunological activity and mucoadhesive properties. They have been used as a mucosal vaccine delivery system for many antigens. This review provides an overview of the recent advances in chitosan nanoparticles as a novel mucosal vaccine delivery system.

کلیدواژه ها:

Adjuvant ، Chitosan Nanoparticle ، Mucosal Vaccine Delivery

نویسندگان

M. Mehrabi

Department of Medical Nanotechnology, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran

H. Montazeri

Department of Medical Nanotechnology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

N. Mohamadpour Dounighi

Department of Human Vaccine and Serum, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran

A. Rashti

Department of Medical Nanotechnology, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran

R. Vakili-Ghartavol

Department of Medical Nanotechnology, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Abruzzo, A., Cerchiara, T., Bigucci, F., Gallucci, M.C., Luppi, B., ...
  • Akagi, T., Baba, M., Akashi, M., ۲۰۰۷. [Development of vaccine ...
  • Akagi, T., Baba, M., Akashi, M., ۲۰۱۲. Biodegradable nanoparticles as ...
  • Amidi, M., Romeijn, S.G., Verhoef, J.C., Junginger, H.E., Bungener, L., ...
  • Aucouturier, J., Dupuis, L., Ganne, V., ۲۰۰۱. Adjuvants designed for ...
  • Bansal, V., Sharma, P.K., Sharma, N., Pal, O.P., Malviya, R., ...
  • Chikaura, H., Nakashima, Y., Fujiwara, Y., Komohara, Y., Takeya, M., ...
  • Deng, Q.-y., Zhou, C.-r., Luo, B.-h., ۲۰۰۶. Preparation and Characterization ...
  • Des Rieux, A., Fievez, V., Garinot, M., Schneider, Y.J., Preat, ...
  • Dyer, A.M., Hinchcliffe, M., Watts, P., Castile, J., Jabbal-Gill, I., ...
  • Fernandez-Urrusuno, R., Calvo, P., Remunan-Lopez, C., Vila-Jato, J.L., Alonso, M.J., ...
  • Islam, M.A., Firdous, J., Choi, Y.J., Yun, C.H., Cho, C.S., ...
  • Kammona, O., Kiparissides, C., ۲۰۱۲. Recent advances in nanocarrier-based mucosal ...
  • Makhlof, A., Tozuka, Y., Takeuchi, H., ۲۰۱۱. Design and evaluation ...
  • Mohammadpourdounighi, N., Behfar, A., Ezabadi, A., Zolfagharian, H., Heydari, M., ...
  • Nandedkar, T.D., ۲۰۰۹. Nanovaccines: recent developments in vaccination. J Biosci ...
  • Neutra, M.R., Kozlowski, P.A., ۲۰۰۶. Mucosal vaccines: the promise and ...
  • Parez, N., Fourgeux, C., Mohamed, A., Dubuquoy, C., Pillot, M., ...
  • Perrie, Y., Mohammed, A.R., Kirby, D.J., McNeil, S.E., Bramwell, V.W., ...
  • Rahimian, S., Fransen, M.F., Kleinovink, J.W., Christensen, J.R., Amidi, M., ...
  • Sandri, G., Bonferoni, M.C., Ferrari, F., Rossi, S., Mori, M., ...
  • Shim, B.S., Choi, Y., Cheon, I.S., Song, M.K., ۲۰۱۳. Sublingual ...
  • Sonaje, K., Chen, Y.J., Chen, H.L., Wey, S.P., Juang, J.H., ...
  • Tonnis, W.F., Kersten, G.F., Frijlink, H.W., Hinrichs, W.L., de Boer, ...
  • Vila, A., Sanchez, A., Janes, K., Behrens, I., Kissel, T., ...
  • Wong, T.W., ۲۰۰۹. Chitosan and its use in design of ...
  • Zhang, L., Zeng, Z., Hu, C., Bellis, S.L., Yang, W., ...
  • Zhang, X., Zhang, H., Wu, Z., Wang, Z., Niu, H., ...
    • نمایش کامل مراجع