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مقالات فارسیISIکنفرانسهاژورنالها

Drug-related Problems Among Type ۲ Diabetic Patients With Hypertension in a Tertiary Care Hospital in Lebanon: A Cross-sectional Study

محل انتشار: مجله تحقیقات دارویی و بیومدیک، دوره: 9، شماره: 3
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 66

فایل این مقاله در 12 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1872284

شناسه ملی سند علمی:

JR_PBRE-9-3_007

تاریخ نمایه سازی: 9 دی 1402

چکیده مقاله:

Background: Patients with type ۲ diabetes (T۲D) often have other associated comorbidities, making them susceptible to drug-related problems (DRPs) which can adversely affect their quality of life. Understanding these problems can provide baseline data to allow informed health decisions and effective management of patients.  Objectives: This study aims to investigate DRPs in T۲D patients with hypertension and find the predictors of these problems.  Methods: This cross-sectional study was conducted for six months in the internal medicine department of a tertiary care hospital in Lebanon. Participants were ۱۳۵ adult T۲D patients with hypertension who were receiving one or more anti-diabetes drugs, and at least one medication for hypertension. Pharmaceutical care network europe classification system was used to classify the DRPs. Data were collected by two clinical pharmacists using a self-report tool. Results: Most of patients were female. Most of them (۹۴.۱%) had at least one DRP (۱.۴۳±۰.۷۲ per patient). “Non-optimal drug treatment effect” was the most frequent problem (۴۸.۲%). Achieving the HbA۱C target reduced the odds of this problem by ۶۶.۶%, while the increased serum creatinine level caused a two-fold increase in this problem. The use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers reduced the odds of DRPs by ۸۶.۲% and ۸۳.۳%, respectively, while lipid-lowering and anti-anginal drug use caused a four-fold increase in DRPs.  Conclusion: Early identification of DRPs in diabetic patients with hypertension and their associated factors can help improve their management and reduce the associated mortality and morbidity rates.

کلیدواژه ها:

Drug-related problems ، Adverse drug reactions ، Type ۲ Diabetes ، Hypertension

نویسندگان

Georges Hatem

Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Hadat, Lebanon.

Aya Awarkeh

Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Hadat, Lebanon.

Lynne H Jaffal

Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Hadat, Lebanon.

Dalia Khachman

Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Hadat, Lebanon.

Amal Al-Hajje

Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Hadat, Lebanon.

Salam Zein

Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Hadat, Lebanon.

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