Effect of Platelet-rich Plasma and Mesenchymal Stem Cells as Two Biological Alternatives in Rotator Cuff Injury Treatment: A Mini-review
محل انتشار: مجله تحقیق در پزشکی مولکولی، دوره: 7، شماره: 3
سال انتشار: 1398
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 57
فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_REMJ-7-3_001
تاریخ نمایه سازی: 22 دی 1402
چکیده مقاله:
The rotator cuff injury is caused by significant damage by trauma or other factors and currently recognized as a prevalent orthopedic problem. Many clinical procedures have been proposed to reduce the complication of rotator cuff injury with varying degrees of success. A literature search was conducted of PubMed and ISI Web of Knowledge using relevant keywords as well as government website for clinical trial. Platelet-rich plasma (PRP) is one of the most effective strategies for the symptomatic treatment of rotator cuff injury. Many parameters can influence the result of PRP, including intensity of rotator cuff injury, patient’s age, PRP producing strategy, and frequency and timing of PRP injections. However, some evidence supports the beneficial effect of PRP in relieving pain and restoring function, along with its minimal adverse effects, compared with using corticosteroids and other nonsurgical methods. Besides platelet-rich plasma, mesenchymal stem cells (MSCs) are another alternative that can be used to treat rotator cuff injuries. Because enough large clinical trials cannot be applied, using these biological cells have their challenges similar to PRP. In conclusion, further research is necessary to understand the potential application of both methods as safe and effective therapeutic options for rotator cuff injuries.
کلیدواژه ها:
نویسندگان
Mohsen Sheykhhasan
Department of Mesenchymal Stem Cell, the Academic Center for Education, Culture and Research, Qom, Iran.
Hamed Manoochehri
Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Pouria Samadi
Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Reza Fotouhi-Ardakani
Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran.
Naser Kalhor
Department of Mesenchymal Stem Cell, the Academic Center for Education, Culture and Research, Qom, Iran.
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :