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مقالات فارسیISIکنفرانسهاژورنالها

Dosimetric Comparison of Fractionated Stereotactic Radiotherapy Plans With And Without Flattening Filter Beams of ۶ MV And ۱۰ MV Beams

محل انتشار: مجله فیزیک پزشکی ایران، دوره: 20، شماره: 5
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 42

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لینک ثابت به این مقاله:
https://civilica.com/doc/1882737

شناسه ملی سند علمی:

JR_IJMP-20-5_008

تاریخ نمایه سازی: 24 دی 1402

چکیده مقاله:

Introduction: It is necessary to understand the importance of different energies in Fractionated Stereotactic Radiotherapy (FSRT) plans for better outcome. The study objective is to compare FSRT plans with Flattening Filter (FF) and Flattening Filter Free (FFF) beams.Material and Methods: Twelve patients with primary Brain Metastasis (BM), were selected and given ۲۵ Gy in five fractions for which ۶FF beams were angled in double arc. The Planning Target Volume (PTV) and Organs at Risk (OARs) were assessed using dosimetric indices after each plan was replanned with ۶ FFF, ۱۰ FF, and ۱۰ FFF energies. Treatment time (TT) and Monitor Units (MUs) were also compared. Additionally, we compared portal dosimetry for dose agreement across all plans using the gamma analysis criterion.Results: PTV parameters of created plans showed better values when compared to ۶ FF plans, where the most significant is with FFF plans which include D۹۸%, D۸۰%, D۲%, D۵۰% and Dose Gradient Index values of ۶FFF plans. Among OARs, the most significant is the V۱۰ value of (Brain-PTV) as (۴۶.۷۷±۴۳.۹) and maximum dose values of optic chiasm, brainstem, and left lens in ۶FFF plans. Among technical parameters, the ۶FFF plan showed significant TT value of (۳.۰۶±۱.۰) with p-value ۴.۱۳E-۰۵. Better gamma analysis passing rates were achieved with FFF beams.Conclusion: Linear accelerator-based FSRT delivery of BM using ۶ FFF beam results in better dosimetric indices, OAR sparing, fastest treatment delivery, and energy conservation with reduced peripheral and out-of-field dose for higher treatment modalities like Rapid arc.

کلیدواژه ها:

VMAT ، Treatment Planning System ، FFF ، Dose Volume Histogram PTV

نویسندگان

Hridya V T

Department of Physics, Research Scholar, Karunya Institute of Technology and Sciences, Coimbatore, India

KHANNA D

Department of Physics, School of Sciences, Arts, Media and Mangement, Karunya Institute of Technology and Sciences, Coimbatore-۶۴۱ ۱۱۴ Tamilnadu India

Aswathi Raj

Department of Physics, Research Scholar, Karunya Institute of Technology and Sciences, Coimbatore, India

Sathish Padmanabhan

Radiation Oncology Department, Senior Consultant, Aster Mims Hospital, Calicut, India

Mohandass P

Chief Medical Physicist Department of Radiation Oncology Fortis Hospital, Sector ۶۲, Phase ۸, SAS Nagar, Mohali-۱۶۰۰۶۲, Punjab India

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