Comparison of the sedative and cardiovascular effects of the combination of acepromazine-clonidine versus acepromazine-xylazine in horses
محل انتشار: گفتمان پژوهش دامپزشکی، دوره: 15، شماره: 1
سال انتشار: 1403
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 54
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شناسه ملی سند علمی:
JR_VRFAN-15-1_004
تاریخ نمایه سازی: 25 دی 1402
چکیده مقاله:
The aim of this study was to compare the sedative and cardiovascular effects of the combination of acepromazine-clonidine versus acepromazine-xylazine in horses. Four healthy cross-bred horses were included in the study. They were assigned to two treatments. In treatment I (T۱), the animals received xylazine hydrochloride (۱.۰۰ mg kg-۱) in combination with acepromazine maleate (۰.۰۵ mg kg-۱) intravenously (IV). In treatment II (T۲), the animals received intra-gastric administration of clonidine (۰.۰۰۲ mg kg-۱) followed by acepromazine (۰.۰۵ mg kg-۱; IV) after ۶۰ min. Head height above the ground (HHAG) and echocardiographic indices were evaluated. In T۱, recordings were made ۵ min before and ۵, ۱۵, ۳۰, ۶۰, and ۹۰ min after drug administration. In T۲, recordings were made ۵ min before clonidine, ۵۵ min after clonidine administration, and then ۵, ۱۵, ۳۰, ۶۰, and ۹۰ min after acepromazine injection. Analyses of the data showed there were not significant differences regarding HHAG and echo-cardiographic indices between two treatments. For sedation of healthy horses, it was concluded that intra-gastric administration of clonidine and IV administration of acepromazine showed similar sedative and cardiovascular effects compared to IV acepromazine-xylazine administration.
کلیدواژه ها:
نویسندگان
Pegah Parhizkar
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
Rahim Mohammadi
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
seyed Mohammad Hashami-Asl
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
Ghader Jalilzadeh-Amin
Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
Farshid Sarrafzadeh-Rezaei
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
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