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مقالات فارسیISIکنفرانسهاژورنالها

Quantification of Lung Tumor Motion and Optimization of Treatment

محل انتشار: مجله فیزیک و مهندسی پزشکی، دوره: 13، شماره: 1
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 52

فایل این مقاله در 12 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1892707

شناسه ملی سند علمی:

JR_JBPE-13-1_008

تاریخ نمایه سازی: 30 دی 1402

چکیده مقاله:

Background: Mobility of lung tumors is induced by respiration and causes inadequate dose coverage. Objective: This study quantified lung tumor motion, velocity, and stability for small (≤۵ cm) and large (>۵ cm) tumors to adapt radiation therapy techniques for lung cancer patients.Material and Methods: In this retrospective study, ۷۰ patients with lung cancer were included that ۵۰ and ۲۰ patients had a small and large gross tumor volume (GTV). To quantify the tumor motion and velocity in the upper lobe (UL) and lower lobe (LL) for the central region (CR) and a peripheral region (PR), the GTV was contoured in all ten respiratory phases, using ۴D-CT. Results: The amplitude of tumor motion was greater in the LL, with motion in the superior-inferior (SI) direction compared to the UL, with an elliptical motion for small and large tumors. Tumor motion was greater in the CR, rather than in the PR, by ۶۳% and ۴۹% in the UL compared to ۵۰% and ۳۸% in the LL, for the left and right lung. The maximum tumor velocity for a small GTV was ۴۴.۱ mm/s in the LL (CR), decreased to ۴ mm/s for both ULs (PR), and a large GTV ranged from ۰.۴ to ۹.۴ mm/s.  Conclusion: The tumor motion and velocity depend on the tumor localization and the greater motion was in the CR for both lobes due to heart contribution. The tumor velocity and stability can help select the best technique for motion management during radiation therapy.

کلیدواژه ها:

Lung Cancer ، Tumor Motion ، Tumor Velocity ، Tumor Stability ، Four-Dimensional Computed Tomography ، Stereotactic Body Radiotherapy ، Radiotherapy ، Intensity-Modulated Radiotherapy

نویسندگان

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Faculty of Medicine, University of Paris-Saclay, ۹۴۲۷۶ Le Kremlin-Bicêtre, France

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MATER Private Hospital, Department of Physics, Eccles Street, Dublin ۷, Ireland

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Center for Radiotherapy, International Medical Centers, Affidea, ۷۸۰۰۰ Banja Luka, Bosnia, and Herzegovina

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Department of Radiation Oncology, Tenon Hospital, APHP, Sorbonne University, ۷۵۰۲۰ Paris, France

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Department of Radiation Oncology, Tenon Hospital, APHP, Sorbonne University, ۷۵۰۲۰ Paris, France

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Department of Radiation Oncology, Tenon Hospital, APHP, Sorbonne University, ۷۵۰۲۰ Paris, France

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  • Lemjabbar-Alaoui H, Hassan OU, Yang YW, Buchanan P. Lung cancer: ...
  • Travis WD, Brambilla E, Riely GJ. New pathologic classification of ...
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