Effect of Viola Odorata Plant Extract on Wound Healing

Introduction: Wound healing is a complex process that involves a series of interconnected cellular and biochemical events aimed at restoring damaged tissues. researchers and scientists are continually exploring new ways to enhance and accelerate this crucial process. In recent years, there has been growing interest in the potential therapeutic properties of plant extracts, including Viola odorata, also known as the sweet violet. This plant possesses a rich history in herbal medicine and studies have shown promising results regarding its ability to facilitate the different stages of wound repair and recovery.Method: Data were obtained by searching keywords in PubMed and Google Scholar from ۲۰۱۷ to ۲۰۲۳.Result: Viola odorata is a small perennial flower from the Violaceae family that contains bioactive compounds such as flavonoids, saponins, alkaloids, and essential oils, which contribute to its potential therapeutic benefits. This plant extract has anti-inflammatory properties that help reduce inflammation and create an optimal environment for healing. This effect can be attributed to its rich content of flavonoids and other bioactive compounds that have anti-inflammatory effects by inhibiting specific signaling pathways in the body. It contains strong antioxidants that fight the damaging effects of free radicals, protecting cells and promoting their regeneration. In addition, Studies have suggested that Viola odorata extract may stimulate collagen synthesis, so promoting wound closure and tissue regeneration. This action can contribute to faster healing and the formation of stronger scars. Also, it exhibits antimicrobial properties due to its bioactive compounds, which can help prevent microbial colonization of wounds and reduce the risk of infection. This natural defense mechanism allows wounds to heal efficiently without complications.Conclusion: Viola odorata has a long-standing reputation in traditional medicine and shows potential as an adjunctive therapy for wound healing. The plant extract's anti-inflammatory, antioxidant, collagen-stimulating, and antimicrobial properties contribute to its effectiveness in promoting wound closure and tissue regeneration. Further research, including clinical trials, is needed to determine the optimal formulation, dosage, and application methods for Viola odorata extract in wound healing treatments. Also, future studies can be performed to determine the molecular mechanisms of Viola odorata in wound healing.