Intensity-Modulated Radiation Therapy (IMRT) Versus Rapidarc in the Treatment of Carcinoma Left Breast – Finding the Optimal Radiation Therapy Technique
محل انتشار: مجله فیزیک پزشکی ایران، دوره: 20، شماره: 6
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 44
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شناسه ملی سند علمی:
JR_IJMP-20-6_006
تاریخ نمایه سازی: 8 بهمن 1402
چکیده مقاله:
Introduction: This study aimed to evaluate the dosimetric variations and treatment efficacy between intensity-modulated radiotherapy (IMRT) and double-arc RapidArc for irradiation of carcinoma left breast, focusing on adequate target coverage, sparing of organs at risk (OARs), delivered monitor units (MUs) per fraction, and treatment delivery time.Material and Methods: This prospective, observational study was conducted on ۳۰ patients with carcinoma left breast. All these patients were treated with adjuvant radiation therapy. We generated two plans for each of these patients: IMRT and double-arc RapidArc technique. The target volume and OARs were analyzed using dose-volume histograms (DVHs). The average MUs and the treatment time were used as markers to assess the efficacy of treatment delivery.Results: The planning target volume parameters such as homogeneity and conformity index were similar for all the plans with both techniques. With IMRT, statistically significantly better sparing of I/L lung, heart, C/L breast, C/L lung, and esophagus were achieved as compared to RapidArc. We found that RapidArc resulted in significantly lower MUs (۵۳۵.۰۵ ± ۱۰۵.۴۲) than IMRT (۹۱۳.۵۷ ± ۱۲۹.۳۵). Treatment delivery time was statistically shorter with RapidArc as compared to IMRT (p=۰.۰۰۱). Conclusion: This study concluded that both IMRT and RapidArc plans have similar target coverage in terms of homogeneity and conformality indexes. Better OARs sparing was noticed with IMRT while RapidArc enabled higher efficacy with lower MUs and shorter treatment delivery time. However, further studies are needed to establish these dosimetric advantages being translated to improvements in the clinical outcomes of these patients.
کلیدواژه ها:
نویسندگان
Preety Negi
Consultant Radiation Oncologist, Capitol hospital, Jalandhar, Punjab, India
Raja Sellapandiyan
Medical Physicist and RSO, Capitol hospital, Jalandhar, Punjab, India
Himanshu Srivastava
Consultant Radiation Oncologist, Capitol hospital, Jalandhar, Punjab, India
Harnoor Pruthi
Consultant Cardiologist, Department of Cardiology, Capitol hospital, Jalandhar, Punjab, India
Gokul Anandhan
Medical Physicist, Capitol hospital, Jalandhar, Punjab, India
Priyanka Singh
DNB Resident, Department of Radiation Oncology, Capitol hospital, Jalandhar, Punjab, India
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