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مقالات فارسیISIکنفرانسهاژورنالها

The Effect of Exercise Trainings in the Stimulation of Brown Adipose Tissue and Transformation of White Adipose Tissue to Brite Adipose Tissue: A Review

محل انتشار: مجله گزارش بهداشت و درمان، دوره: 2، شماره: 4
سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 64

فایل این مقاله در 16 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1907854

شناسه ملی سند علمی:

JR_RHCA-2-4_008

تاریخ نمایه سازی: 24 بهمن 1402

چکیده مقاله:

There are three types of adipose tissue in the human body: white adipose tissue (WAT), brown adipose tissue (BAT) and beige or Brite adipose tissue. In WAT, energy reserves in the form of triglyceride, while in BAT triglyceride molecules lipolyze for thermogenesis through fatty acid oxidation. A protein called uncoupling protein-۱ (UCP۱) is responsible for non-shivering thermogenesis in BAT. The most important activators of BAT include peroxisome proliferator-activated receptor gamma coactivator ۱-alpha (PGC-۱α), sympathetic nervous system (SNS), hypothalamic–pituitary–thyroid axis (HPT axis), endothelium, atrial natriuretic peptides, irisin, β-aminoisobutyric acid (BAIBA), Fibroblast growth factor ۲۱ (FGF۲۱) and interleukin-۶ (IL۶) that generally exert their effects through stimulation of UCP۱ expression and activity. Beige adipose are among white adipose and elevation of UCP۱ gene expression is the main cause of their production that atrial natriuretic peptides, PGC۱α, irisin, FGF۲۱ and BAIBA are the most stimulators of this transformation. The role of exercise in the stimulation of BAT and transformation of WAT to Brite is discussed in this study.

کلیدواژه ها:

Training ، Adipose Tissue

نویسندگان

Mohsen Jafari

Department of Sport Sciences, Shirvan Branch, Islamic Azad University, Shirvan, Iran

Mehrdad Fathi

Department of Exercise Physiology, Ferdowsi University of Mashhad, Mashhad, Iran

Elham Pouryamehr

Department of Sport Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran

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