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مقالات فارسیISIکنفرانسهاژورنالها

هیدروژل های هوشمند حساس به محرک: به عنوان بستری جذاب در کاربردهای درمانی

محل انتشار: مجله دانشگاه علوم پزشکی مازندران، دوره: 33، شماره: 228
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: فارسی
مشاهده: 118

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استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1911466

شناسه ملی سند علمی:

JR_JMUMS-33-228_017

تاریخ نمایه سازی: 27 بهمن 1402

چکیده مقاله:

هیدروژل ها به دلیل خواص منحصربه فرد خود مانند محتوای آب بالا، نرمی، انعطاف پذیری و زیست سازگاری بسیار محبوب شده اند. در همین راستا کاربردهای فراوانی را در پزشکی پیدا کرده اند. از میان ساختارهای مختلف هیدروژلی می توان به هیدروژل های هوشمند اشاره کرد. این ساختارها توانایی پاسخ به محرک های محیطی را دارند. محرک های محیطی می توانند فیزیکی، شامل دما و یا شیمیایی مانند  pHباشند. در این مطالعه کاربرد هیدروژل های هوشمند در زمینه های دارو، ژن و پروتئین رسانی و مهندسی بافت تقسیم بندی شده است. نتایج مطالعه نشان می دهد که انواع مختلفی از هیدروژل های هوشمند شناسایی شده اند که دارای قابلیت های گوناگون می باشند. در حال حاضر، هیدروژل ها برای ساخت عدسی های تماسی، محصولات بهداشتی، داربست های مهندسی بافت، سامانه های دارو رسانی و پانسمان زخم استفاده می شوند و بیش ترین مطالعه در زمینه دارو رسانی هوشمند به ویژه در داروهای ضد سرطان مورد بررسی قرارگرفته است و همچنین در زمینه مهندسی بافت که می توان به نتایج مطلوب تری در آینده نزدیک رسید.

کلیدواژه ها:

نویسندگان

فاطمه فرجادیان

Associate Professor, Pharmaceutical Sciences Research Center, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran

فاطمه محسنی

Pharmd, Students Research Committee, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran

امین رئیسی

Pharmd, Students Research Committee, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran

راضیه ثابت

Assistant Professor, Department of Medicinal Chemistry, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran

سعید دانش آموز

Associate Professor, Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran

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