Evaluation and impact of omega-۳ supplementation with a period of selective aerobic exercise on liver enzymes (AST-ALT) of active student girls

Introduction: Liver enzymes are among clinical and biochemical parameters reflecting liver function in muscle exercises and Aspartate amino transferase (AST) and Alanine aminotransferase (ALT) enzymes are indicators of liver damage in sporting activities. However, AST and ALT liver enzymes are affected by supplementation with omega-۳. In the present study, the effects of omega-۳ supplementation in combination with a selective aerobic activity on liver enzymes (AST and ALT) in trained female students were examined for ۶ weeks. Methods: For this purpose, ۳۲ person among Female students in physical education in Alzahra University, between age ۲۲.۵±۱.۲ years with a body mass index ۲۱.۵۹±۱.۲ kg/m۲ were selected and randomly divided into ۴ groups: control, supplements, exercise and supplementation with aerobic exercise group. AST and ALT measurements was done at pre-test and post-test. Data was analyzed using paired t-test, ANOVA and Paried t-test. Results: The results showed that inter-group and between-group changes in AST values in some groups was significant. AST levels were significantly reduced in supplementation with aerobic exercise group whereas ALT levels were significantly increased in all groups except the control group, but no significant changes in ALT levels between the groups was seen. Conclusion: AST significant differences between the exercise group and supplementation with aerobic exercise group represent a possible beneficial effect of supplementation with aerobic exercise. This effect is probably due to changes in cell membrane fluidity, or changes in liver metabolism in the liver. Seems likely for decrease in ALT, longer time or higher doses are needed.