The Accuracy of Sanitary Pad of Nitrazine Test in the Diagnosis of Premature Rupture of Membranes

Background: Sanitary Pad of Nitrazine Test (SPONT) is one of the newest method to diagnosis premature rupture of membranes (PROM) that doesn't need women attending hospital and applying speculum. The aim of this study was to assess the performance of SPONT versus standard clinical assessment.Methods: A prospective diagnostic accuracy study, ۱۴۰ pregnant women with symptoms of PROM in ۲۲-۴۲ weeks of gestation were involved. The accuracy of SPONT in the diagnosis of PROM was compared with Nitrazine, Fern and Pooling tests that were performed at the same time.Results: The sensitivity, specificity, positive predictive value, and negative predictive value of SPONT, routine Nitrazine, Fern and Pooling tests were ۹۳.۲%, ۸۵.۷%, ۹۷.۳%, ۶۹.۲%; ۹۴.۱%, ۹۰.۵%, ۹۸.۲% ۷۳.۱%; ۸۰.۱%, ۹۵.۲%, ۹۸.۹%, ۴۶.۵%; and ۶۸.۱%, ۹۵.۲%, ۹۸.۹% ۴۶.۵%, respectively. The sensitivity of SPONT was the same as routine Nitrazine test (P.V=۰.۸۱۱). SPONT has higher sensitivity than Fern test (P.V=۰.۰۰۸) and Pooling test (P.V<۰.۰۰۱). The accuracy of the applied tests was ۹۲.۱%, ۹۳.۶%, ۸۲.۸% and ۷۲.۸% respectively for SPONT, Nitrazine, Fern and Pooling tests. There wasn't significant difference between accuracy of SPONT and standard clinical assessment (۹۲.۱% vs. ۸۹.۳%).Conclusions: The accuracy of SPONT was the same as routine Nitrazine test in PROM diagnosis that pregnant women can use it if they do not have immediate access to health centers.Background: Sanitary Pad of Nitrazine Test (SPONT) is one of the newest method to diagnosis premature rupture of membranes (PROM) that doesn't need women attending hospital and applying speculum. The aim of this study was to assess the performance of SPONT versus standard clinical assessment. Methods: A prospective diagnostic accuracy study, ۱۴۰ pregnant women with symptoms of PROM in ۲۲-۴۲ weeks of gestation were involved. The accuracy of SPONT in the diagnosis of PROM was compared with Nitrazine, Fern and Pooling tests that were performed at the same time. Results: The sensitivity, specificity, positive predictive value, and negative predictive value of SPONT, routine Nitrazine, Fern and Pooling tests were ۹۳.۲%, ۸۵.۷%, ۹۷.۳%, ۶۹.۲%; ۹۴.۱%, ۹۰.۵%, ۹۸.۲% ۷۳.۱%; ۸۰.۱%, ۹۵.۲%, ۹۸.۹%, ۴۶.۵%; and ۶۸.۱%, ۹۵.۲%, ۹۸.۹% ۴۶.۵%, respectively. The sensitivity of SPONT was the same as routine Nitrazine test (P.V=۰.۸۱۱). SPONT has higher sensitivity than Fern test (P.V=۰.۰۰۸) and Pooling test (P.V<۰.۰۰۱). The accuracy of the applied tests was ۹۲.۱%, ۹۳.۶%, ۸۲.۸% and ۷۲.۸% respectively for SPONT, Nitrazine, Fern and Pooling tests. There wasn't significant difference between accuracy of SPONT and standard clinical assessment (۹۲.۱% vs. ۸۹.۳%). Conclusions: The accuracy of SPONT was the same as routine Nitrazine test in PROM diagnosis that pregnant women can use it if they do not have immediate access to health centers.