Candida Species Isolated from Various Clinical Samples and Their Susceptibility Patterns to Antifungals
سال انتشار: 1392
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 29
فایل این مقاله در 5 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JMMI-1-1_004
تاریخ نمایه سازی: 29 بهمن 1402
چکیده مقاله:
Candida is an asexual, diploid, dimorphic fungus that is present on human body and his environment. Nowadays the number of patients, who are immunocompromised, aged, receiving prolonged antibacterial and aggressive cancer chemotherapy or undergoing invasive surgical procedures and organ transplantation, is on increase, and therefore candidiasis emerged itself as an alarming opportunistic disease. The aim of this study is to identify the most common Candida species in clinical samples, and their antifungal susceptibility patterns. During a cross-sectional study performed in the Department of Microbiology and Serology, Narayana Hrudayalaya Hospitals (India) from January to December ۲۰۱۲, some ۲۱۳ fungal isolates from various samples were collected. All the isolates were identified to the species level, using Vitek ۲ YST identification card (bioMerieux, France). Antifungal sensitivity was performed against amphotericin B (AMB), ۵ flucytosine (۵-FC), fluconazole (FLU) and voriconazole (VOR) using ASTYS۰۶ (bioMerieux, France). The majority of the isolates were from urine (۴۸%) followed by respiratory (۱۷%) and blood samples (۱۶%). The most common species among the ۲۱۳ isolates were Candida tropicalis (۵۶%) followed by Candida albicans (۳۳%). Non-albicans Candida species are emerging as the major pathogens and mainly seen in patients on prolonged ventilation and central lines. Antifungal agents should be used cautiously due to increased resistance seen in these agents.
کلیدواژه ها:
نویسندگان
Sankarankutty Jaya
Department of Microbiology and Serology, Narayana Hrudayalaya Hospital, Bangalore, India
Vipparti Harita
Department of Microbiology, Malla Reddy Institute of Medical Science, Dr. NTR University, Hyderabad, Andhra Pradesh
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :