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مقالات فارسیISIکنفرانسهاژورنالها

Innate Immunity Plays a Key Role in Leishmania Infection: Implications for Vaccine Design

محل انتشار: مجله میکروبیولوژی پزشکی و بیماریهای عفونی، دوره: 4، شماره: 3
سال انتشار: 1395
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 35

فایل این مقاله در 6 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:
https://civilica.com/doc/1917748

شناسه ملی سند علمی:

JR_JMMI-4-3_001

تاریخ نمایه سازی: 29 بهمن 1402

چکیده مقاله:

Neutrophils are part of the first line of immune response and are essential for resistance against a variety of pathogens. They professionally mediate direct killing of pathogens, recruit other phagocytes by specific chemokines, produce cytokines and interact with different immune cells to shape the adaptive response. Leishmania as an obligatory intracellular parasite has evolved to benefit this early innate response to find its way into macrophages, the final host cells. Therefore it is important to reconsider the role of neutrophils for further improvement of the current vaccine status.

کلیدواژه ها:

Innate immunity ، Neutrophil ، Leishmania ، Vaccine

نویسندگان

Negar Seyed

Department of Immunotherapy and Leishmania Vaccine Research, Pasteur Institute of Iran, Tehran, Iran

Sima Rafati

Department of Immunotherapy and Leishmania Vaccine Research, Pasteur Institute of Iran, Tehran, Iran

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