Urinary tract co-infections in patients with papillomavirus

BACKGROUND AND OBJECTIVESHuman papillomavirus (HPV) has been identified the etiologic agent of warts, cervical intraepithelial neoplasia (CIN), and cervical cancer. Among sexually transmitted infections (STIs), only HPV infection is known to be a major cause of cervical cancer.This virus is a type of DNA virus that mainly affects epithelial cells of the skin and mucous membranes.HPV virus is divided into high-risk and low-risk types. Most HPV infections, especially the low-risk types, are transient and are eliminated by the host and immune system after a while, but some of these infections can persist and become malignant, which indicates that there are other factors that can have synergistic effect with this virus and cause the transformation of normal cervical epithelial cells into cancer cells.Aside from HPV, other bacterial infections in the genital tract are associated with cervical neoplasia Such as Ureaplasma spp and Neisseria gonorrhoeae.The purpose of this study is to investigate bacterial co-infections with HPV virus and their role in causing cervical cancer in order to reduce Getting this disease.MATERIALS AND METHODSThe studies were conducted as a review of related articles.RESULTS AND DISCUSSIONResearchers believe that the simultaneous infection of different types of HPV virus with some factors such as bacteria can increase the risk of malignancy.They also found that the presence of some bacteria (Ureaplasma, Chlamydia, and Gardnerella) in the lower part of the female genital system has a positive correlation with the frequency of HPV infection and, consequently, a possible influence on faster progression to cervical dysplasia caused by HPV.CONCLUSIONResearchers Found that the presence of some bacteria (Ureaplasma, Chlamydia, and Gardnerella) in the lower part of the female genital system affect the frequency of HPV infection and, consequently can affect the faster progression to cervical dysplasia.