Prevalence of asymptomatic bacteriuria, antibiotic resistance pattern and related factors in pregnant women referring to Gonabad Community Health Centers

BACKGROUND AND OBJECTIVESUrinary tract infection is the most common bacterial infection during pregnancy that can present as asymptomatic bacteriuria, cystitis or pyelonephritis. This study was performed to evaluate the prevalence of asymptomatic bacteriuria, antibiotic resistance pattern and related factors in pregnant women referring to Gonabad community health centers in ۲۰۱۹.MATERIALS AND METHODSThis study is a cross-sectional study. In this study, ۲۹۵ pregnant women referring to Gonabad community health centers participated from April ۲۰۱۹ to March ۲۰۲۰. Laboratory and demographic information of the samples were extracted from the Sib system and laboratories data base in Gonabad. Statistical analysis was performed using SPSS ۱۶.۰ software and descriptive and inferential statistics. The acceptable p-value was considered ۰.۰۵.RESULTS AND DISCUSSIONThe results showed that ۱۰.۵ % of pregnant women had asymptomatic bacteriuria. Significant relationship was observed between asymptomatic bacteriuria and history of abortion(P=۰.۰۱۸), anemia(P=۰.۰۰۸) and age (P=۰.۰۱۲), but no significant relationship was observed between asymptomatic bacteriuria and the manner of last delivery, gravidity, multi-fetal condition, body mass index, education, occupation and blood group (P> ۰.۵). The most common organism of asymptomatic bacteriuria was Escherichia coli (۶۷.۷%) and then Coagulase-negative Staphylococcus (۱۶.۱%). The most appropriate antibiotic was Nitrofurantoin, to which ۹۰.۳% of organisms were sensitive.CONCLUSIONAsymptomatic bacteriuria in pregnancy is a common problem in Gonabad. Due to its side effects, it is recommended to re-culture urine in high-risk individuals at regular intervals during pregnancy and treat it with appropriate drugs to reduce maternal and fetal complications