Prolonged Fever and Coronary Artery Involvements: Kawasaki Disease or Systemic Juvenile Idiopathic Arthritis?
محل انتشار: مجله پزشکی بالینی، دوره: 10، شماره: 3
سال انتشار: 1402
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 33
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شناسه ملی سند علمی:
JR_RCM-10-3_005
تاریخ نمایه سازی: 13 اسفند 1402
چکیده مقاله:
Introduction: The symptoms and laboratory findings of Kawasaki disease (KD) and systemic-onset juvenile idiopathic arthritis (SoJIA) may overlap in the early phases. Coronary artery lesions are common complications seen in KD.Cases Presentation: In this article, we report three cases of SoJIA (two males and one female) with prolonged relapsing fever and coronary artery involvement. Initially, all three cases were presumed to have KD and were treated with IVIG. All three cases had arthritis and lymphadenopathy, and one of them had a skin rash. After ۳-۸ weeks, fever and main clinical symptoms returned. In the second evaluation, they met the criteria for SoJIA and were treated with methylprednisolone, ibuprofen, and methotrexate. High ferritin levels were observed in all three cases (mean=۶۰۲۴ ng/ml).Conclusion: Coronary artery involvement may rarely be seen in the early phases of SoJIA. Continuing or relapsing fever, late-onset arthritis, and increased serum ferritin levels may help distinguish SoJIA from KD.
کلیدواژه ها:
نویسندگان
Mehrnaz Olfat
Children’s Medical Center, Pediatric Center of Excellence, Tehran, Iran
Raheleh Assari
Children’s Medical Center, Pediatric Center of Excellence, Tehran, Iran
Mohamad-Taghi Majnoon
Children’s Medical Center, Pediatric Center of Excellence, Tehran, Iran
Vahid Ziaee
Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran