Determination of the serum level of aluminum & zinc in hemodialysis patients in Kerman,Iran

Dialysis is one of the effective methods which has been used since ۱۹۵۵ for the treatment of patients suffering from renal failure( more often of its chronic type). The dialysis results in the elimination of waste materials like urea and creatinine from the body, on the other hand, it can affect the serum contamination of the dialysis fluid. Aluminium is one of trace elements which its serum level increases in patient undergoing hemodialysis. This increase of serum concentration of aluminium, effects the metabolism of iron. In this study, the serum level of aluminium and zinc in patients subjected to hemodialysis were evaluated. The subjects were ۵۶ hemodialysis patient and the control were ۳۶ healthy appearing people. Aluminium and zinc serum concentration determined using flameless atomic absorption spectroscopy. The results indicated that: ۱) the mean serum concentration of aluminium( ۰.۲۷۲+_۰.۱۲۸ ppm) shows a significant increase in  the patient group, compared with the control group (۰.۰۱۶+_۰.۰۰۵ ppm) ( p<۰.۰۵).  ۲) the mean serum concentration  of zinc (۰.۸۰۶+_۰.۱۷۷ ppm) in these patients shows no significant increase compared with control group (۰.۷۶۷+_۰.۱۵۹ ppm).